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Epidemiology - MIDTERM 2 > Topic 41 - Disease caused by astroviruses > Flashcards

Topic 41 - Disease caused by astroviruses Flashcards

1
Q

Which disease can be caused by astrovirus?

A

Avian nephritis
Duck hepatitis
Astrovirus disease of Turkey

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2
Q

Which virus does astroviriade family belong under?

A

Picornavirus

This is the most important picornavirus

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3
Q

Name the two genus of Astroviridae:

A
  1. Mamostravirus
  2. Avastrovirus
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4
Q

Which of the two genus of astroviridae is most important for us?

A

Nr 2: Avastrovirus

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5
Q

Which genus causes avian nephritis?

A

Avastrovirus

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6
Q

Are astroviruses enveloped or non-enveloped?

A

Non-enveloped

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7
Q

Is astroviruses RNA or DNA viruses?

A

RNA viruses

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8
Q

World occurence of avian nephritis:

A

Widespread

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9
Q

Does avian nephritis have virulence variants?

A

yes

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10
Q

How is avian nephritis spread?

A

By faeces in large numbers

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11
Q

Susceptible species of avian nephritis:

A

Only chickens!!

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12
Q

Age group affected by avian nephritis:

A

Any age group

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13
Q

Age group where clinical signs can be seen in case of avian nephritis:

A

First month of life

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14
Q

Mortality rate of avian nephritis:

A

1-10% for the first week, after it decreses

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15
Q

Why can clinical signs become more severe in case of avian nephritis?

A

If immunosuppressive effects are present

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16
Q

Route of infection in case of avian nephritis:

A

Per os

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17
Q

Where does replication happen in case of avian nephritis?

A

In the gut epithelium

18
Q

Pathogenesis of avian nephritis:

A

Infection causes vireaemia, the virus will then reach the kidney, where there will be a second replication. There will be an inflammation, a interstitial nephritis.

19
Q

Where does the second replication take place in case of avian nephritis?

A

In the epithelial cells of the proximal tubules

20
Q

Interstitial nephritis will cause what, in case of avian nephritis?

A

The function of the kidney will be decreased and uricosis will happen

21
Q

Does avian nephritis have good or bad antigen?

A

Good.
It has a good immune response, resulting in good maternal immunity

22
Q

Which age group have more severe clinical signs in case of avian nephritis?

A

Young animals
Day-old chickens

23
Q

Acute clinical signs in day-old chickens in case of avian nephritis:

A

they are not specific, general clinical signs will be shown from day 3

24
Q

Due to viraemia, which clinical signs can we see in day-old chickens in case of avian nephritis?

A
  1. Diarrhoea
  2. Kidney lesions
  3. Uricosis
  4. Decreased weight gain
  5. Growth retadation
25
Q

Clinical signs of chronic form in day-old chickens when infected with avian nephritis:

A
  1. Visceral urate deposits
  2. Death
26
Q

Pathological lesions in case of avian nephritis

A
  1. Enteritis
  2. Interstitial nephritis: swelling, paleness
27
Q

Pathological lesions in case of chronic form of avian nephritis

A

Urate deposition = uricosis

28
Q

Which methods do we use to diagnose avian nephritis?

A
  1. Epidemiological rules
  2. Clinical signs
  3. Pathology
  4. Histopathology

but also detection of the virus: RT-PCR, ELISA

29
Q

Differential diagnosis of avian nephritis:

A

Nephropathogenic strains of infectious bronchitis virus

30
Q

Prevention methods for avian nephritis:

A
  1. General epidemiological rules
31
Q

Is there a vaccine for avian nephritis?

A

NO

32
Q

Causative agent of duck hepatitis caused by astrovirus:

A

Avastrovirus genus under astroviridae family - picorna virus

33
Q

How many serotypes for duck hepatitis caused by astrovirus?

A

Two.

duck astrovirus 1 and 2

34
Q

Clinicals signs for duck hepatitis caused by astrovirus:

A

same as duck hepatitis caused by avihepatovirus

35
Q

Diagnosis and prevention for duck hepatitis caused by astrovirus?

A

same as duck hepatitis caused by avihepatovirus

36
Q

Causative agent of astrovirus disease of turkey:

A

Avastrovirus genus under astroviridae family - picorna virus

37
Q

How many serotypes does astrovirus disease of turkey have?

A

Two

38
Q

Occurence of astrovirus disease of turkey:

A

Worldwide

39
Q

Clinical signs of astrovirus disease of turkey:

A

Diarrhoea in 1-5 week old turkeys

40
Q

Clinical signs for astrovirus disease of turkey:

A

Same as avian nephritis

41
Q

Prevention measures for astrovirus disease of turkey:

A

General epidemiological rules

Epidemiology - MIDTERM 2 (35 decks)

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