PQS - African swine fever Flashcards
Several virulence variants of African Swine Fever Virus exist
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Very, moderately and weakly
African swine fever is shed in the saliva of the infected animals
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+ nasal discharge
Stamping out of the infected herds is applied in the control of African Swine Fever
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The leading clinical sign in African swine fever is excess salivation
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Haemorrhages
In acute African swine fever the leading pathological findings are the haemorrhages
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The African swine fever infects the swine per os
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The African swine fever virus genome codes only 2 proteins
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The African swine fever virus infects the swine by air
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In African swine fever cases of abortion are never observed
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Abortion always happens
The primary replication site of African swine fever virus is the oronasal mucosa.
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In tonsilla, regional lymph node
The tick species vectoring African swine fever are present in Portugal and Spain
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The ASF virus is serologically uniform but several genotypes exist
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In acute ASF we can observe high mortality in sows
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Vaccines are available in EU to be used in the control of African swine fever
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Vaccines are available to be used in the control of ASF
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The immune system cannot neutralize the ASF virus by antibodies
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No neutralizing antibodies are produced
The African swine fever virus can be disinfected by 2%NaOh within 1 day
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5% hypochlorite is needed
In Europe the main route of infection is the transmission of the African swine fever by ticks
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Only in southern Europe - Spain and Portugal
The African swine fever virus is highly resistant against the environmental conditions
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The African swine fever causes hemadsorption in cell cultures
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In the control of African swine fever thinning of the wild boar populations is helpful
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ASF is always a peracute disease
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ASF virus retains its infectivity for years in frozen meat
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The African swine fever virus replicated in lymphocytes
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Only in Leuckocytes, monocytes and macrophages
Wild boars may be chronically infected with African swine fever virus
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Wild boars can carry African Swine Fever virus as chronically infected animals
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African swine fever is endemic in Sardinia
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ASF virus is shed in the urine of the infected animals
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The primary replication sites of African swine fever virus are the tonsils and lymph nodes
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In acute ASF cases the leading pathological finding is the black and enlarged lymph nodes
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In case of African swine fever enlarged spleen is observed during necropsy.
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The ASF virus replicates the bone marrow
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The tick species vectoring African swine fever are present in Portugal and Spain
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The resistance of the African swine fever virus is very low
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The exemption of the “thumb rule” of enveloped/non-enveloped viruses
African swine fever is generally transmitted by mosquitoes
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Tick in southern countries and oral infection
African swine fever can cause disease in humans
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The African swine fever virus can be inactivated by irradiation
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African Swine Fever virus infects every cloven hoofed animal
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Only swine and wild boars/warthogs
African Swine Fever does not occur in Europe.
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African Swine Fever is a resistant virus.
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Immunocomplexes are formed in the case of African Swine Fever
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It is the ultimate outcome of AFV
Only activated vaccines are used for the prevention of African Swine Fever.
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NO vaccines available
Ticks can transmit African Swine Fever virus
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In ASF cases abortion is never observed
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In general: abortion ALWAYS happens
Swine and wild boars are susceptible to African Swine Fever virus.
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Warthogs can maintain African Swine Fever in endemic areas
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Attenuated vaccines are used for the prevention of African swine fever
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African Swine Fever virus has a low resistance
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African Swine Fever virus can infect pigs and wild boars
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The clinical signs of African Swine Fever are more severe in wild boars than in farmed pigs.
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There is a widespread vaccination in endemic areas to prevent African Swine Fever
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In Europe the ticks are the most important means in the transmission of the ASF virus.
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Oral infection
In case of ASF infection viremia can last for months
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Infection by moderately virulent ASF virus results in high mortality of sows
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90-100%, closer to 100%
The moderately virulent ASF virus does not cause fever.
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Fever is due to the viraemia!!
In case of infection by highly virulent ASF virus we can see skin necrosis as clinical sign.
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Causes peracute disease = rapid death, without pathological findings or clinical signs
Can see skin necrosis in chronic form, mild virulent strain
In chronic cases of ASF spleen hyperplasia is a leading pathological lesion
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African swine fever leads to abortion regardless of the virulence of the infecting virus
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Wild boars may carry African Swine Fever virus as chronically infected animals
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The main tool against African Swine Fever is vaccination
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Virulent strains of African Swine Fever virus cause an acute disease in domestic pigs.
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Acute disease = moderate strain
Acute African Swine Fever is characterized by haemorrhages.
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Vaccination is used for prevention of African Swine Fever.
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African Swine Fever cause skin lesions in swine
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Chronic form causes ulcers in skin
African Swine Fever is caused by arbovirus.
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African Swine Fever is endemic in Central Europe.
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Endemic in Sardinia
African Swine Fever virus infects pigs and ruminants.
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Only pigs
African Swine Fever virus can replicate in certain ticks.
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In soft ticks
African Swine Fever is caused by any arbovirus.
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African Swine Fever is a notifiable disease
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Virus neutralization is the most important tool for African Swine Fever diagnosis.
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Pregnant sows abort in case of African Swine Fever disease cases.
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The chronic form of African Swine Fever is similar to other immune complex disorders
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African Swine Fever infection of humans leads to cold like symptoms.
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African Swine Fever virus may cause chronic infections in pigs.
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African Swine Fever may cause a chronic disease in wild boars.
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African swine fever virus can replicate in certain soft ticks.
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The clinical picture of chronic African Swine Fever is similar to dermatitis Nephritis/nephropathy.
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African Swine Fever does not have any vaccination.
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The ASF virus can be detected by hemagglutination test
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The boutons in the intestines are characteristic pathological findings in case of ASF
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This is the case of Classical swine fever
Several virulence variants of ASF virus exist
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