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IMS > Topic 2 (Epithelium) > Flashcards

Topic 2 (Epithelium) Flashcards

1
Q

What does the epithelium sit on?

A

sits on basal lamina

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2
Q

Term definition that epithelium have to rely on with regards to diffusion

A

Avascular

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3
Q

Name 2 areas that epithelia is found

A

Airways (trachea)

Sweat glands (skin)

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4
Q

Tight junction seals what?

What protein is involved

A

Protein movement

Occuludin protein

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5
Q

Adherens junction functin

A

Connects cells together across cytoskeletons

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6
Q

Gap junction do what?

A

Communication between cells

Allows ion exchange to occur

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7
Q

what does desmosomes do

A

Adhere cells together

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8
Q

If epithelial are in multiple layers, what is this called?

A

Stratified

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9
Q

Cells at the top of the layer give what?

A

The overall shape of the cells

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10
Q

what type of cells can you find with pseudo-stratified cells?

A

Cilia / Goblet

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11
Q

Where can you find transitional layer

A

Areas of distention

Bladder / urinary

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12
Q

What is the purpose of keratinisation

A

Protection

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13
Q

Where can you find layer of keratin (4)

A

Oesophagus / skin / vagina / bladder

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14
Q

In gaseous diffusion areas, is it single or stratified?

A

Single squamous

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15
Q

What does the endothelium produce to prevent adhesion of platelets?

What produces it?

A

Prostacyclin

Prostacyclin synthase

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16
Q

What does SMC release for relaxation? For contractioN?

A

NO

Endothelium-1

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17
Q

What does the endothelium release which is found in blood clotting?

A

Tissue factor

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18
Q

What is found on the surface on endothelium cells to help facilitate trans endothelial migration

A

E-selectin

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19
Q

What lines all body cavities?

A

Mesothelium

20
Q

What type of cells is found in the mesothelium

A

Simple unilayer epithelium

21
Q

role of mesothelium

A

surface lubrication

22
Q

What does the ectoderm form? (2)

A

Nervous system

Exoskeleton

23
Q

What type of cell is found in secretion?

A

Goblet

24
Q

Difference between exocrine and endocrine

A

Exocrine releases substances onto surface

Endocrine releases into BS

25
Q

if a gland is branched, what is it called?

A

Compound gland

26
Q

If a gland isnt branched, what is it called?

A

simple

27
Q

Simple tubular glands can be found where?

A

Intestines

28
Q

Simple coiled glands can be found where?

A

Sweat glands (skin)

29
Q

Simple tubular branched glands can be found where (4)

A

Stomach / uterus / tongue / oesophagus

30
Q

Simple alveolar glands can be found where

A

sebaceous glands on skin

31
Q

Compound Tubular glands can be found where?

A

Oral cavity

32
Q

Compound alveolar can be found where?

A

Pancreatic glands

33
Q

Compound tubular acinar can be found where?

A

mammary gland

34
Q

Merocrine secretion involves what?

give 2 examples of merocrine secretion

A

vesicle fuses with membrane / recycled

Pancreatic enzymes
Breast milk casein

35
Q

Apocrine secretion involves what?

Name an example of secretion

A

Plasma membrane lost with vesicle fusion

Breast milk lipids

36
Q

Holocrine secretion involves what?

Name an example

A

Product accumulates in cell and released with disintegration of cell

Sebum in sebaceous glands

37
Q

What is Epidermolysis bullosa

A

Inherited blistering of skin

38
Q

Causes of Epidermolysis bullosa

A

Mutation of adhesion molecule found for epithilium to BM

39
Q

what is cystic fibrosis

A

defective chloride channel on apical surface of epithelial cells

40
Q

Cause of cystic fibrosis

A

Mutations in CFTR

41
Q

What builds up in CF patients? (2)

A

Cl- in cells

Mucous builds up outside cells

42
Q

Where can CF occur?

A

Any exocrine glands

Pancreas / lungs

43
Q

What is Congenital cilliary dyskinesia

A

abnormal cilia function

44
Q

Cause of congenital cililary dyskinesia

A

autosomal recessive

45
Q

Symptoms (2) of congenital ciliary dyskinesia

A

Respiratory issues

sinusitis

IMS (25 decks)

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