Topic 2- Antigens Flashcards
Every cell in the human body has 1._____ on it which allow the body to identify it
- Markers
True or false: Microorganisms (both pathogenic and non-pathogenic), such as bacteria and viruses, also have their own unique markers
True
What is the formal name for these markers?
Antigens
What is the function of antigens?
allow cell-to-cell recognition
Where are antigens found?
cell surface membranes, bacterial cell walls, or the surfaces of viruses
Which molecules found on the cell membrane’s outer surface can act as antigens?
-Glycolipids
-Glycoproteins
What are the 2 types of antigens?
-Self antigens
-Non-self antigens
Define self-antigens
Antigens produced by the organism’s own body cells (those that the immune system does not recognise as foreign antigens)
What do self-antigens NOT stimulate?
A specific immune response
Define non self antigens
Antigens not produced by the organism’s own body cells (those that the immune system recognises as being foreign
What do non-self antigens stimulate?
An immune response
What causes antigen variability?
genetic mutations
Why is antigen variability a problem for the immune system?
-The surface receptors on lymphocytes and memory cells are complementary in shape to only one antigen
-When the antigen on a pathogen changes the lymphocytes and memory cells can no longer bind
-As a result, there is no secondary immune response
-The host gets infected and suffers from the disease again