Antibodies

Question 1

Antibodies are 1.____ glycoproteins called 2.______

Answer 1

1.globular
2.immunoglobulins

Question 2

What is the structure of antibodies?

Answer 2

-Quaternery structure
-Two heavy Polypeptider chains
-Disulfide bonds
-Two light polypeptide chains
-Y shape

Question 3

What two regions do polypeptides have?

Answer 3

-Constant region
-Variable region

Question 4

The constant regions do not vary within a class (isotype) of antibodies but do vary between what?

Answer 4

Classes

Question 5

What does the constant region determine?

Answer 5

the mechanism used to destroy the antigens

Question 6

What are different in the variable region of each antibody?

Answer 6

Amino acid sequence

Question 7

Which region is where the antibody attaches to the antigen to form an antigen-antibody complex?

Answer 7

Variable

Question 8

What site is at the end of the variable region?

Answer 8

Antigen- binding site

Question 9

The antigen-binding sites 1._____ greatly give the antibody its 2.____ for binding to antigens. The sites are specific to the epitope (the part of the antigen that binds to the antibody)

Answer 9

1.vary
2.specificity

Question 10

What is the hinge region?

Answer 10

where the disulfide bonds join the heavy chains

Question 11

What does the hinge region allow for?

Answer 11

flexibility to the antibody molecule which allows the antigen-binding site to be placed at different angles when binding to antigens