Topic 19: Nervous System Flashcards
what are the 2 divisions of the nervous system?
-central nervous system (CNS)
-peripheral nervous system (PNS)
what is the central nervous system?
-command center
-brain + spinal cord
-processes + integrates info
what does the peripheral nervous system consist of?
-cranial nerves
-spinal nerves
where do the cranial nerves go?
-to/from the brain
where do the spinal nerves go?
-to/from the spinal cord
what are the 2 divisions of the PNS?
-sensory/afferent division
-motor/efferent division
what is the sensory/afferent division of the PNS?
-arriving/going in to the CNS
-has sensory receptors that detect stimuli
-stimuli = changes in the internal/external environments
what is the motor/efferent division of the PNS?
-exiting/going out of the CNS
-nerves convey impulses away from the CNS
-innervates (supplies nerves to) effectors
what are effectors?
-muscles
-glands (exocrine or endocrine)
what are the 2 cells in the nervous system?
-neurons
-neuroglia (glial cells)
what are neurons?
-cells that conduct impulses
-make up the CNS + PNS
-mostly amitotic (irreplaceable)
what is the structure of a neuron?
-cell body
-cell body processes (dendrites + axon)
-can be very long, but are very small in diameter
which neurons are able to be replaced?
-taste
-olfaction
-memory
what are the characteristics of the cell body of a neuron?
-contain typical organelles
-rough ER is called nissl bodies
-clusters of cell bodies in the CNS = nuclei (gray matter)
-clusters of cell bodies in the PNS = ganglia
what is the purpose of dendrites?
-receive incoming messages + relay them to the cell body
what is the purpose of the axon?
-carry impulses away from the cell body
what are the parts of an axon?
-axon hillock
-axon terminal
what is the axon hillock?
-where the axon meets the cell body
what is the axon terminal?
-typically branched with synaptic end bulbs (enlarged tips)
- at the end of the axon
what can change between axons?
-can be myelinated or unmyelinated
what does it mean for an axon to be myelinated?
-wrapped in many layers of cell membrane (myelin sheath)
-has electrical insulation (can conduct electrical impulses)
what are gaps in the myelin sheath called?
-nodes of ranvier
what are the cells that make up the myelin sheath in the CNS? PNS?
-oligodendrocytes (CNS)
-schwann cells (PNS)
where are there myelinated axon bundles?
-CNS = tracts (white matter)
-PNS = nerves
what are unmyelinated neurons?
-no myelin sheath
what are neuroglia (glial cells)?
-support neuron cells
-can undergo mitosis to be replaced
-prone to cancer/brain tumors
what are the 2 types of neuroglia (glial cells)?
-CNS neuroglia
-PNS neuroglia
what are the glial cells of the CNS?
-oligodendrocytes
-microglia
-astrocytes
-ependymal (neural epithelia)
what is the purpose of oligodendrocytes?
-produce myelin around the axon
what is the purpose/function of microglia?
-protective
-become phagocytic if infected, dead or damaged neurons are detected
-immune cells cannot enter the CNS
what is the purpose of astrocytes?
-surround blood capillaries to form part of the blood brain barrier
-control capillary permeability of what is leaving + going to the brain
what is the purpose of ependymal (neural epithelia)?
-line brain ventricles + central canal of the spinal cord
-secrete cerebrospinal fluid (CSF) + circulate it (cillia)
what are the glial cells of the PNS?
-schwann cells
-satellite cells
what is the purpose of schwann cells?
-form myelin around axons in the PNS
what is the purpose of satellite cells?
-surround neuron cell bodies in ganglia
-protect + support
what are the structural types of neurons? what are they based on?
-unipolar
-bipolar
-multipolar
-based on the # of cell processses
what are unipolar neurons?
-have 1 continuous process that divides into 2 (central and peripheral portions)
-peripheral end has dendrites (interact with sensory receptors for pain, touch, etc)
-central end is the axon
-always sensory neurons
what are bipolar neurons?
-2 processes
-1 axon, 1 process with dendrites
-sensory (retina + nose (olfaction) )
what are multipolar neurons?
-3 or more processes
-1 axon + many dendrites
-all interneurons + motor neurons
-most common
what are the 3 functional types of neurons?
-sensory/afferent neurons
-interneurons
-motor/efferent neurons
what are sensory/afferent neurons?
-mostly unipolar
-go from the sensory receptors to the CNS
what are interneurons?
-within the CNS
-between sensory + motor
-99% of neurons
-mostly multipolar
what are motor/efferent neurons?
-CNS to effectors
-all multipolar
what are the different neuron junctions?
-neuronal junction
-neuromuscular junction
-neuroglandular junction
what are neuronal junctions?
-neuron to neuron
-can be chemical (use neurotransmitters)
-can be electrical (use ions)
what are neuromuscular junctions?
-motor neuron to skeletal muscle
what are neuroglandular junctions?
-motor neuron to gland
what are the most common neuronal synapses?
-chemical neuronal synapses
what is the structure of a chemical neuronal synapse?
-presynaptic neuron
-axon terminal
-synaptic cleft
-postsynaptic neuron
what is the presynaptic neuron?
-neuron bringing the impulse
what is the purpose of the axon terminal in chemical synapses?
-the synaptic end bulbs (presynaptic membrane) has synaptic vesicles
-synaptic vesicles contain a neurotransmitter that will be diffused through the synaptic cleft fluid
what is the synaptic cleft?
-space between neurons
what is the postsynaptic neuron?
-receives the impulse
-has a postsynaptic membrane
-cell membrane of dendrites or a cell body with receptor sites for the neurotransmitter
what are the protective features of the central nervous system?
-bone
-meninges
-cerebrospinal fluid (CSF)
-blood brain barrier
-cerebral arterial circle
what is the bone that protects the CNS?
-the skull + vertebral column
what are meninges?
-CT around the brain + spinal cord
-3 layers
what are the layers of meninges?
-dura mater (outer)
-arachnoid mater (middle)
-pia mater (inner)
what are the characteristics of the dura mater in the brain?
-2 fused layers
-separated in spots to form spaces = venous (dural) sinuses (brain only)
-these sinuses contain blood
what is deep to the dura mater for both the brain + the spinal cord?
-subdural space
-filled with ISF
what are the characteristics of the dura mater in the spinal cord?
-1 layer
-superficial to the dura mater is the epidural space (spinal cord only)
-space is filled with fat, blood vessels, CT, etc (spinal cord only)
what are the characteristics of the arachnoid mater in the brain?
-avascular
-subarachnoid space
-has arachnoid granulations (brain only)
what are the characteristics of the arachnoid mater in the spinal cord?
-avascular
-subarachnoid space
what is the subarachnoid space?
-contains cerebrospinal fluid (CSF)
-web like strands of CT to secure it to the pia mater below
what are arachnoid granulations?
-project into the dural sinuses
-cerebrospinal fluid (CSF) enters the granulations to return to the blood
what are the characteristics of the pia mater in the brain and spinal cord?
-on the surface of the CNS
-vascular
what is meningitis?
-inflammation of meninges
what is cerebrospinal fluid (CSF)
-surrounds the brain + spinal cord
-in the brain ventricles + central canal of spinal cord
-cushions the CNS (brain buoyant=floats)
what forms and produced cerebrospinal fluid (CSF)?
-formed from blood plasma (similar composition)
-produced by choroid plexuses (networks) (blood capillaries) found in each ventricle
what are the brain ventricles?
-spaces inside the brain (filled with CSF)
-2 lateral ventricles (1st + 2nd)
-3rd + 4th ventricles
where are each of the brain ventricles?
-1st + 2nd = cerebrum
-3rd = diencephalon
-4th = surrounded by pons, medulla oblongata, cerebrum
what is the central canal of the spinal cord?
-space in the spinal cord
what cells make the blood brain barrier?
-endothelial cells (of capillaries) with tight junctions
-astrocytes with foot processes wrap around the endothelial cells
how does the blood brain barrier let stuff through?
-selectively permeable
-allows glucose + fat soluble material
-does not allow toxins, antibiotics, etc
what is the cerebral arterial circle?
-cerebral arteries form a circle at the base of the forebrain
what structures does the cerebral arterial circle circle?
-pituitary gland
-optic chiasma (where optic nerves cross)
what does the cerebral arterial circle unite?
-unites the two major blood supplies to the brain (anterior + posterior)
what does the cerebral arterial circle provide?
-an alternate route for blood if the vessels are blocked
what are the 3 divisions of the brain/
-forebrain
-midbrain
-hindbrain
what is the cerebrum?
-right + left cerebral hemispheres
-everything superior + anterior to the cerebellum
what are the lobes of the cerebrum? how are they named?
-frontal
-temporal
-parietal
-occipital
-insula (deep to temporal)
-named after the cranial bones
what are the surface features of the cerebrum?
-fissures (deep grooves)
-gyri (ridges)
-sulci (shallow grooves)
what are the 3 fissures of the cerebrum?
-longitudinal fissure
-transverse fissure
-lateral fissure
what do each of the fissures seperate?
-long. = right + left cerebral hemispheres
-trans. = cerebellum + cerebrum
-lat. = temporal lobe from the rest of the cerebrum
what are two examples of gyri in the cerebrum?
-postcentral gyrus in the parietal lobe
-precentral gyrus in the frontal lobe
what separates gyri?
-sulci
what is an example of a sulci in the cerebrum?
-central sulcus between frontal + parietal lobes
what are the 3 layers of the cerebrum?
-cerebral cortex
-tracts
-basal nuclei