THYROID GLAND & METABOLISM Flashcards

1
Q

Lipophilic hormones are primarily produced by the:______
Gallbladder
Liver
Pancreas
Kidney

A

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

HPT axis stands for

A

Hypothalamus anterior pituitary thyroid axis
(Pathway for thyroid hormones)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

In HPT axis the hypothalamus releases :_____ hormone

A

Thyrotropin releasing hormone (TRH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

In HPT axis the anterior pituitary releases ____ hormone

A

Thyroid stimulating hormone (TSH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

C cells of thyroid gland release :
Adrenaline
Calcitonin
TSH
TRH

A

Calcitonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Follicular cells of thyroid gland secrete _____ hormone.
Calcitonin
Glycoprotein
Neurotransmitter
Thyroid hormone
Follicular hormone

A

Thyroid hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Colloid of thyroid gland is a _____
Receptor
Hormone
Ion channel
Glycoprotein

A

Glycoprotein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Thyroid hormone is 2 hormones: T3(___) and T4(___)
Membrane of the ____ hormone class

A

Triiodothyronine and tetraiodothyronine
Tyrosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tyrosine synthesized in body but _____ must be obtained from the diet, which is a halogen

A

Iodine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Order synthesis of thyroid hormones steps:
A. Iodine is co-transported into cell with Na+ and transported into colloid couple = T3 & T4
B. Follicular cell synthesizes enzymes and thyroglobulin for colloid
C. Thyroid peroxidase oxidizes iodide ions, MIT/DIT’s
D. Intracellular enzymes separate T3&T4 from protein
E. Thyroglobulin taken back into cell

A

B, a, c, e, d

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Is T3 or T4 the principle thyroid hormone ?

A

T3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Every step of thyroid hormone synthesis and secretion is controlled by this hormone from the anterior pituitary

A

TSH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

TSH production is controlled by this hormone from the hypothalamus

A

TRH Thyrotropin releasing hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

This hormone maintain structural integrity of the thyroid gland
-deficiency causes atrophy of gland
- excess TSH produces y per trophy and hyperplasia of follicular cells
- enlarged thyroid called a goiter

A

TSH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

An enlarged thyroid is called a ____

A

Goiter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

_____= an estimate of an individuals basal energy expenditure required to maintain vital function; usually measured after a 12 hour fast in a resting state

A

BMR

17
Q

BMR stands for ____

A

Basal metabolic rate

18
Q

Thyroid hormones have differential effects on intermediate metabolism depending on level of production: which one is catabolic and anabolic ?

-for normal adults the net effect is _____
- pathologically high amounts cause futile cycles of metabolism ; the net effect is______

A

Anabolic
catabolic

19
Q

Are thyroid hormones permissive or restrictive for GH activity ?

A

Permissive

20
Q

Low secretion of thyroid hormones = _____

A

Hypothyroidism

21
Q

Excess secretion of thyroid hormones =___

A

Hyperthyroidism