Female Reproduction II Flashcards

1
Q

_____ duct development in the female proceeds in the absence of of androgenic steroids and mullerian inhibiting factor (MIF)

A

Mullerian

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2
Q

_____ are a diploid cell population in the embryonic female ovary that undergo mitosis to create the lifetime pool of ova (oocytes)

A

Oogonia

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3
Q

Oogonia are a diploid cell population in the embryonic female ovary that undergo ______ to create the lifetime pool of ova (oocytes)

A

Mitosis

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4
Q

___________ describes the process by which the female gamete (oocyte) develop

A

Oogenesis

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5
Q

_____ status: twice the number of unique chromosomes (2N = 46 human cells)

A

Diploid

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6
Q

_______ status : number of unique chromosomes (N=23 for human gametes )

A

Haploid

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7
Q

This stage of meiosis is when the germ cell is in gonads

A

Prophase 1

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8
Q

Segregation occurs at this phase of meiosis 1

A

Anaphase 1

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9
Q

This phase of meiosis 11 produces 4 haploid gametes

A

Telophase 11

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10
Q

_________: a programmed cell death process for unselected oocyte and its companion follicle cells

A

Atresia

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11
Q

__________: a diploid oocyte that has started the process of meiosis, but is arrested in meiosis I ; MI is completed before ovulation

A

Primary oocyte

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12
Q

__________: a haploid oocyte that is arrested in meiosis II: it is the secondary oocyte that is ovulated. MII is completed only when a sperm fuses with the oocyte

A

Secondary oocyte

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13
Q

Hormones from the ____ and ______ trigger steroid production y cells of the ovary, follicle maturation and oocyte ovulation all in a cyclic pattern (average 28 day cycle)

A

Hypothalamus
Anterior pituitary gland

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14
Q

HPG stands for

A

Hypothalamic pituitary gonadal axis

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15
Q

_______ peptide hormone : GNRH- gonadotropin releasing hormone

A

Hypothalamic peptide hormone

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16
Q

_______ hormone: FSH- follicle stimulating hormone
LH- luteinizing hormone

A

Anterior pituitary peptide hormone

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17
Q

_______ onset approx 12 years of age in girls

A

Pubertal

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18
Q

Rising estrogen concentrations in the late follicular phase selectively repress ____ ( combined with the action of inhibit, another peptide hormone from the ovary) = strong negative feedback

A

FSH

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19
Q

High _____ concentrations of the late follicular phase stimulate LH release = positive feedback leading to the LH surge

A

Estrogen

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20
Q

LH target what cells ?

A

Thecal

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21
Q

FSH targets what cells?

A

Granulosa cells

22
Q

Androgens diffuse from thecal cells into_____ cells

A

granulosa

23
Q

The growing oocytes are surrounded by a matrix that is called the _______

A

Zone pellucida (ZP)

24
Q

Growing oocytes are surrounded by a matrix , the zone pellucida
This is apart of what phase ?

A

Follicular

25
Q

Granules cells secrete estrogen systemically and into the growing follicle
This is apart of what phase ?

A

Follicular

26
Q

_____ reinitiates meiosis in the primary oocyte, to the point of arrest in MII

A

LH

27
Q

_____ arrests estrogen synthesis in granulosa cells (sudden concentration drop)

A

LH

28
Q

____ triggers vascular changes and swelling to promote follicle rupture and oocyte release (ovulation)

A

LH

29
Q

Ovulated secondary oocyte has complete MI arrested in MII
This is apart of what phase ?

A

Ovulation

30
Q

What day of cycle is the follicular phase ?

A

1-13

31
Q

What day of cycle is the Ovulation phase ?

A

14

32
Q

Oocyte is surrounded by ZP and a Halo of granulosa cells and oocyte is captured by fimbriae of the oviduct
What phase does this occur

A

Ovulation

33
Q

What day of cycle is Early literal phase ?

A

15-22

34
Q

Remaining granulosa cells luteinize and form the corpus luteum
What phase does this occur?

A

Early luteal

35
Q

Produces high levels of steroid hormones progesterone and estrogen. Prepares endometrial layer ready for an embryo to implant
What phase does this occur?

A

Early luteal

36
Q

In the early luteal phase remaining granulosa cells “luteinize” and form the _____

A

Corpus luteum

37
Q

The uterus consists of______ (outer smooth muscle) and_______ (inner lining of epithelial cells, blood vessels and glands)

A

Myometrium
Endometrium

38
Q

High ____ concentrations in the follicular have rimes the endometrium, (PR) to respond to progesterone in the secretory phase

A

Estrogen

39
Q

High estrogen concentrations in the follicular phase primes the _____ to respond to progesterone in the secretory phase

A

Endometrium

40
Q

In the ____ phase the endometrial layer becomes loose and water filled (edamatous). Highly vascularized and glycogen loaded, suitable for implant implantation

A

Secretory

41
Q

In the secretory phase the ________ becomes loose and water filled , highly vascularized and glycogen loaded; suitable for embryo implantation

A

Endometrial layer

42
Q

In the secretory phase the endometrial layer becomes loose and water filled , highly vascularized and glycogen loaded; suitable for _________

A

Embryo implantation

43
Q

What day of cycle does the late luteal phase occur ?

A

24-28

44
Q

In the absence of embryo implantation , corpus luteum has a finite period of hormone-producing activity ; degenerates to corpus alibi and and estrogen & progesterone levels fall
What phase does this occur ?

A

Late luteal

45
Q

What phase is the endometrial layer shed ?

A

Late luteal phase

46
Q

What happens to FSH and LH in the late luteal phase ?

A

Rise

47
Q

Is the number of primary follicles in the female ovary at birth infinite or finite?

A

Finite

48
Q

Once the follicle number is drastically reduced the ovarian cycle becomes irregular and then ceases, this occurs at around 50 years of age and is known as

A

Menopause

49
Q

Menopause is correlated to drastically reduced ___ levels

A

Estrogen

50
Q

Drastically reduced ____ levels associated with :
- end of fertility
- reduced bone- building capacity
- reduced vasomotor control (hot flashes)
All symptoms of _____

A

Estrogen
Menopause