Female Reproduction II Flashcards

1
Q

_____ duct development in the female proceeds in the absence of of androgenic steroids and mullerian inhibiting factor (MIF)

A

Mullerian

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2
Q

_____ are a diploid cell population in the embryonic female ovary that undergo mitosis to create the lifetime pool of ova (oocytes)

A

Oogonia

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3
Q

Oogonia are a diploid cell population in the embryonic female ovary that undergo ______ to create the lifetime pool of ova (oocytes)

A

Mitosis

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4
Q

___________ describes the process by which the female gamete (oocyte) develop

A

Oogenesis

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5
Q

_____ status: twice the number of unique chromosomes (2N = 46 human cells)

A

Diploid

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6
Q

_______ status : number of unique chromosomes (N=23 for human gametes )

A

Haploid

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7
Q

This stage of meiosis is when the germ cell is in gonads

A

Prophase 1

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8
Q

Segregation occurs at this phase of meiosis 1

A

Anaphase 1

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9
Q

This phase of meiosis 11 produces 4 haploid gametes

A

Telophase 11

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10
Q

_________: a programmed cell death process for unselected oocyte and its companion follicle cells

A

Atresia

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11
Q

__________: a diploid oocyte that has started the process of meiosis, but is arrested in meiosis I ; MI is completed before ovulation

A

Primary oocyte

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12
Q

__________: a haploid oocyte that is arrested in meiosis II: it is the secondary oocyte that is ovulated. MII is completed only when a sperm fuses with the oocyte

A

Secondary oocyte

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13
Q

Hormones from the ____ and ______ trigger steroid production y cells of the ovary, follicle maturation and oocyte ovulation all in a cyclic pattern (average 28 day cycle)

A

Hypothalamus
Anterior pituitary gland

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14
Q

HPG stands for

A

Hypothalamic pituitary gonadal axis

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15
Q

_______ peptide hormone : GNRH- gonadotropin releasing hormone

A

Hypothalamic peptide hormone

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16
Q

_______ hormone: FSH- follicle stimulating hormone
LH- luteinizing hormone

A

Anterior pituitary peptide hormone

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17
Q

_______ onset approx 12 years of age in girls

A

Pubertal

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18
Q

Rising estrogen concentrations in the late follicular phase selectively repress ____ ( combined with the action of inhibit, another peptide hormone from the ovary) = strong negative feedback

A

FSH

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19
Q

High _____ concentrations of the late follicular phase stimulate LH release = positive feedback leading to the LH surge

A

Estrogen

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20
Q

LH target what cells ?

A

Thecal

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21
Q

FSH targets what cells?

A

Granulosa cells

22
Q

Androgens diffuse from thecal cells into_____ cells

23
Q

The growing oocytes are surrounded by a matrix that is called the _______

A

Zone pellucida (ZP)

24
Q

Growing oocytes are surrounded by a matrix , the zone pellucida
This is apart of what phase ?

A

Follicular

25
Granules cells secrete estrogen systemically and into the growing follicle This is apart of what phase ?
Follicular
26
_____ reinitiates meiosis in the primary oocyte, to the point of arrest in MII
LH
27
_____ arrests estrogen synthesis in granulosa cells (sudden concentration drop)
LH
28
____ triggers vascular changes and swelling to promote follicle rupture and oocyte release (ovulation)
LH
29
Ovulated secondary oocyte has complete MI arrested in MII This is apart of what phase ?
Ovulation
30
What day of cycle is the follicular phase ?
1-13
31
What day of cycle is the Ovulation phase ?
14
32
Oocyte is surrounded by ZP and a Halo of granulosa cells and oocyte is captured by fimbriae of the oviduct What phase does this occur
Ovulation
33
What day of cycle is Early literal phase ?
15-22
34
Remaining granulosa cells luteinize and form the corpus luteum What phase does this occur?
Early luteal
35
Produces high levels of steroid hormones progesterone and estrogen. Prepares endometrial layer ready for an embryo to implant What phase does this occur?
Early luteal
36
In the early luteal phase remaining granulosa cells “luteinize” and form the _____
Corpus luteum
37
The uterus consists of______ (outer smooth muscle) and_______ (inner lining of epithelial cells, blood vessels and glands)
Myometrium Endometrium
38
High ____ concentrations in the follicular have rimes the endometrium, (PR) to respond to progesterone in the secretory phase
Estrogen
39
High estrogen concentrations in the follicular phase primes the _____ to respond to progesterone in the secretory phase
Endometrium
40
In the ____ phase the endometrial layer becomes loose and water filled (edamatous). Highly vascularized and glycogen loaded, suitable for implant implantation
Secretory
41
In the secretory phase the ________ becomes loose and water filled , highly vascularized and glycogen loaded; suitable for embryo implantation
Endometrial layer
42
In the secretory phase the endometrial layer becomes loose and water filled , highly vascularized and glycogen loaded; suitable for _________
Embryo implantation
43
What day of cycle does the late luteal phase occur ?
24-28
44
In the absence of embryo implantation , corpus luteum has a finite period of hormone-producing activity ; degenerates to corpus alibi and and estrogen & progesterone levels fall What phase does this occur ?
Late luteal
45
What phase is the endometrial layer shed ?
Late luteal phase
46
What happens to FSH and LH in the late luteal phase ?
Rise
47
Is the number of primary follicles in the female ovary at birth infinite or finite?
Finite
48
Once the follicle number is drastically reduced the ovarian cycle becomes irregular and then ceases, this occurs at around 50 years of age and is known as
Menopause
49
Menopause is correlated to drastically reduced ___ levels
Estrogen
50
Drastically reduced ____ levels associated with : - end of fertility - reduced bone- building capacity - reduced vasomotor control (hot flashes) All symptoms of _____
Estrogen Menopause