THE ENDOCRINE PANCREAS Flashcards
Functional anatomy of the pancreas :
98% ___
-digestive enzymes and bicarbonate
-secreted through pancreatic duct
2%_____
-peptide hormones regulate glucose and other intermediary metabolism
-secreted by Exocytosis-drains into hepatic portal vein
Exocrine
Endocrine
Duct cells and Acinar cells in pancreas are the _____ portion of the pancreas
Exocrine
Which cells secrete aqueous NaHCO3 solution and which secrete digestive enzymes :
Duct cells
Hormones
Blood
Alpha cells
Acinar cells
Pancreatic polypeptide cells
Duct and acinar
Hormones and islets of langerhans are apart of which portion of pancreas?
Endocrine
What’re the 2 hormones found in the pancreas ?
Adrenaline
Norepinephrine
Insulin
Glycogen
Glucagon
Epinephrine
Insulin \
Glucagon
Alpha cells secrete:
Somatostatin
Insulin, amylin
Glucagon
Glucose
D cells
Glucagon
Beta cells secrete:
Somatostatin
Insulin, amylin
Glucagon
Glucose
D cells
Insulin amylin
D cells secrete:
Somatostatin
Insulin, amylin
Glucagon
Glucose
Alpha cells
Somatostatin
What cells secrete pancreatic polypeptide
Beta
Alpha
D
Pp
Pp
_______-stimulates uptake and storage of energy substrates
1. Insulin
2 glucagon
3 somatostatin
4 pancreatic polypeptide
Insulin
______- stimulates production of glucose by liver
1. Insulin
2 glucagon
3 somatostatin
4 pancreatic polypeptide
Glucagon
_____- general inhibition of exocrine and endocrine pancreatic secretion : acts in paracrine fashion
1. Insulin
2 glucagon
3 somatostatin
4 pancreatic polypeptide
Somatostatin
_____- inhibition of exocrine pancreatic secretion
1. Insulin
2 glucagon
3 somatostatin
4 pancreatic polypeptide
Pancreatic polypeptide
Role of pancreatic hormones is to provide constant supply of _____ to CNS
Glucose
The ____ state - first hours after eating
The ______ state - between meals
1 postabsorptive
2 absorptive
3 steady
4 homeostatic
Absorptive
Postabsorptive
Insulin and glucagon secretion are controlled by ____ concentration
Blood glucose
Does glucose absorption from digestive tract increase or decrease blood glucose ?
Increase
Does hepatic glucose production :
- Through glycogenolysis of stopped glycogen
- through gluconeogenesis
Increase or decrease blood glucose ?
Increase