Male Reproduction Flashcards
The _____ is the primary reproductive organ(males) that produces immature gametes (spermatozoa )
Testes
_____ duct development in the male proceeds in the presence of androgenic steroids and mullerian inhibiting factor (MIF)
Wolffian
Wolffian duct development in the male proceeds in the presence of androgenic steroids and __________
Mullerian inhibiting factor (MIF)
During the later months of gestation the testes descend into the scrotum under the influence of _____
Testosterone
_________ describes the entire process of male gamete (spermatozoan) development
Spermatogenesis
________ status: twice the number of unique chromosomes (2N=46 for human cells )
Diploid status would have n or 2n ?
2n
How many chromosomes for diploid status ?
46
_____ status: number of unique chromosomes (N=23 for human gametes )
Haploid
Does haploid status have n or 2n ?
N
How many chromosomes for haploid status?
23
_______ are a diploid cell population in the male testis that undergo mitosis and over the male lifespan, providing a continuous supply of cells for gamete development
Spermatogonia
Spermatogonia are a _____ cell population in the male testis that undergo mitosis and over the male lifespan, providing a continuous supply of cells for gamete development
Diploid
Spermatogonia are a diploid cell population in the male ____ that undergo mitosis and over the male lifespan, providing a continuous supply of cells for gamete development
Testis
Spermatogonia are a diploid cell population in the male testis that undergo _____ and over the male lifespan, providing a continuous supply of cells for gamete development
Mitosis
Spermatogonia are a diploid cell population in the male testis that undergo mitosis and over the male lifespan, providing a continuous supply of cells for _____development
Gamete
______: a diploid cell derived by mitosis of Spermatogonia progenitor cells
Primary spermatocyte
Primary spermatocyte is a diploid cell derived by _____ of Spermatogonia progenitor cells
Mitosis
Primary spermatocyte is a diploid cell derived by mitosis of________ cells
Spermatogonia progenitor
Primary spermatocyte is A diploid cell derived
by mitosis of spermatogonial progenitor cells;
primary spermatocytes enter _____
Meiosis
______ is a haploid cell ( doubled dna strands) resulting from the completion of MI
Secondary spermatocyte
Secondary spermatocyte is a_____ cell (doubled dna strands) resulting from the completion of MI
Haploid
Secondary spermatocyte is a haploid cell (doubled dna strands) resulting from the completion of ____
MI
______ is a haploid cell (single dna strands) resulting from completion of MII
Spermatid
Spermatid is a haploid cell (single dna strands) resulting from completion of ____
MII
Spermatid is a___ cell (single dna strands) resulting from completion of MII
Haploid
_______ is a haploid gamete that has undergone specialized morphological change (by process of spermiogenesis )
Spermatozoan
Spermatozoan is a _____ gamete that has undergone specialized morphological change (by process of spermiogenesis )
Haploid
Spermatozoan is a haploid gamete that has undergone specialized morphological change (by process of_______ )
spermiogenesis
Sertoli cells are within or outside Of seminiferous tubules ?
Within
Leydig cells are within or outside Of seminiferous tubules ?
Outside
Are sertoli or leydig cells within the seminiferous tubules?
Sertoli
Are sertoli or leydig cells outside the seminiferous tubules?
Leydig
_____ cells are supporting cells of the testes and are present within the seminiferous tubules
Sertoli
Cell body of Sertoli cells spans from the perimeter of the tubule to the ____
Lumen
Adjacent Sertoli cells attached by _____: cell-cell barrier to prevent immune cell-mediated reactions against proteins (antigens) unique to spermatogenesis
Tight junctions
Sertoli cells are present within the _______
Seminiferous tubules
______ barrier (akin to BBB, but sertoli-cell mediated)
Blood testis
Sertoli cells provide nutrients to developing ____
Spermatozoa
Sertoli cells have ____ function by engulfing excess cytoplasm shed via Spermatid remodelling and any abnormal gametes
Phagocytic
Sertoli cells have phagocytic function by engulfing excess ____ shed via Spermatid remodelling and any abnormal gametes
Cytoplasm
Sertoli cells secrete fluid into the ____ of the tubule to flush immobile sperm to the epididymis for maturation
Lumen
Sertoli cells secrete _____ to bind testosterone and keep local concentration ver high in the tubules
Antigen binding protein (ABP)
_____ cells are supporting cells of the testis and are prone t BETWEEN the seminiferous tubules
Leydig
____ cells produce testosterone under the influence of LH from the anterior pituitary gland
Leydig
Leydig cells produce ___ under the influence of LH from the anterior pituitary
Testosterone
Leydig cells produce testosterone under the influence of __ from the anterior pituitary
LH
Leydig cells produce testosterone under the influence of LH from the _____ gland
Anterior pituitary
_____ is the process of morphological transformation of the round Spermatid into a specialized form
Spermiogenesis
Spermiogenesis is the process of morphological transformation of the round ____ into a specialized form
Spermatid
Spermatozoa complete their maturation in the ____ they are also stored ad concentrated there
Epididymis
______complete their maturation in the epididymis where they are also stored and concentrated
Spermatozoa
What are the 4 parts of a mature spermatozoan ?
Acrosome
Nucleus
Mitochondria
Microtubules
What part is within the head portion of a spermatozoan?
Mitochondria
Nucleus
Microtubules
Acrosome
Acrosome
Nucleus
What part is within the mid piece portion of a spermatozoan?
Mitochondria
Nucleus
Microtubules
Acrosome
Mitochondria
What part is within the tail (flagellum) portion of a spermatozoan?
Mitochondria
Nucleus
Microtubules
Acrosome
Microtubules
The tail of a mature spermatozoan is also called the ___
Flagellum
Optimal temperature for spermatogenesis in ____degrees less tan body temperature
2/3
Testes hang lower or retract towards the abdomen in a muscular reflex according to external ____ changes
Temperature
This muscle controls the retracting/lowering of the testes according to external temperature changes
Cremaster
This component of the male reproductive system is a pair located in scrotum, and produces sperm + secretes testosterone
Testis
The ____ is a skin-covered sac suspended within the angle between the legs
Scrotum
The _____ and _____ are a pair that serve as sperms exit route from the testes and serve as a tie for maturation of sperm for motility and fertility as well as concentrate/store sperm
Epididymis and ductus deferens
The ____ is a pair tat both empty into the last portion of the ductus deferens, one on each side. It supplies fructose to nourish the ejaculated sperm, secretes prostaglandins that stimulate motility to help transport sperm within male and female. Provides the bulk of semen and as well as precursors for the clotting of semen
Seminal vesicles
The ____ gland completely surrounds the urethra at the neck of the bladder and secretes alkaline fluid that neutralizes the acidic vaginal secretions and triggers clotting of the semen to keep sperm in the vagina during penis withdrawal
Prostate
_________ gland is a pair that empty into the urethra (one on each side ) just before the urethra enters the penis and secretes mucus for lubrication
Bulbourethral
Spermatozoa + secretions of accessory sex organs = _____
Semen
Ph of semen is normally >_____
7.1
Color of semen is normally ____
White light yellowish
Time to liquify semen is normally ___ minutes
60
Volume of semen is normally ___ mL after 5 day abstinence
1.5
Concentration of semen is normally an average of ___ million/mL
15
The _______ axis controls GNRH and FSH+LH
Hypothalamic pituitary gonadal (HPG)
The HPG axis :
Hypothalamic peptide hormone :______
Anterior pituitary peptide hormones: ______+ _____
GNRH
FSH + LH
LH acts on ___ cells to produce testosterone
Leydig
___ acts on leydig cells to produce testosterone
Lh
Lh acts on ;ending cells to produce ____
Testosterone
Testosterone (T) and FSH acts on ___ cells to support spermatogenesis
Sertoli
Testosterone (T) and FSH acts on sertoli cells to support______
spermatogenesis
__ and ___ act on Sertoli cells to support spermatogenesis
T and FSH
T & LH production inhibin from Sertoli cells on FSH is a ___ feedback
Neg
_____ characteristics are those that distinguish males and females , established and maintained by reproductive hormones
Secondary sex