Pregnancy And Paturition Flashcards
The endometrium is maintained in the secretory phase by ___ and ___ secreted by the corpus luteum following ovulation
Estrogen
Progesterone
The endometrium is maintained in the secretory phase by estrogen and progesterone secreted by the ______following ovulation
Corpus luteum
The endometrium is maintained in the secretory phase by estrogen and progesterone secreted by the corpus luteum following ______
Ovulation
Mitosis of of zygote begins when zygote is retained in the ____
Oviduct/ Fallopian tube
The_______ is the form the early embryo takes BEFORE implanting into the endometrium
Blastocyst
The last step before the embryo can attach to the endometrium is called ______ where the blastocyst breaks out of the zone pellucida
Hatching
The last step before the embryo can attach to the endometrium is called hatching where the blastocyst breaks out of the ______
Zone pellucida
Uterine _____ takes place about 6-7 days following fertilization
Implantation
A _________ is when an embryo implants anywhere besides the uterus and therefore cannot be carried to term
Ectopic pregnancy
The trophoblast layer enzymatically invades the endometrium to release ____ and begins the process of ____ development
Nutrients
Placenta
The __________ layer enzymatically invades the endometrium(decidua) to release nutrients and begins the process of placenta development
Trophoblast
The trophoblast cells secrete a hormone _____, known as the pregnancy hormone at high concentration
HCG
HUMAN CHORIONIC GONADOTROPIN
____ is secreted in the urine = basis for the early pregnancy test
HCG
Human chorionic gonadotropin
HCG. Production is necessary to prevent _____ and to support early stages of ______
Menstruation
Pregnancy
____ production is necessary to prevent menstruation and to support the early stages of pregnancy
HCG
____ sustains hormone production of the corpus luteum before fetus and placenta take over estrogen and progesterone production
HCG
HCG binds to __ receptors of the ____ cells in embryonic testis to stimulate testosterone production
LH
Leydig
HCG binds to LH receptors of the leydig cells in embryonic testis to stimulate______ production
testosterone
The human gestation period is __ weeks
38
Organ systems and human form are established by ___ weeks of development (embryo to fetal)
8
The human fetus develops within the _____
Amniotic sac
The ____ is a fetal membrane developed form extra embryonic tissues
Amnion
The amnion grows with the fetus eventually filling the _____
Uterine cavity
The amnion is filled with ______
Amniotic fluid
The amnion is filled with amniotic fluid and is ___ and ____ by the fetus
Swallowed and urinated
_____ in the amnion is swallowed and urinated by the fetus
Amniotic fluid
How does the amnion support the fetus ?
Buoyancy
Protect against infection
Temperature control
The ______ contains blood vessels that transport blood between fetus and placenta
Umbilical cord
The umbilical contains _____ that transport blood between fetus and placenta
Blood vessels
The umbilical cord contains blood vessels that transport ___ between fetus and placenta
Blood
________ carries oxygenated blog and nutrients from placenta to fetus
Umbilical vein
_____ carry deoxygenated blood and waste products from fetus to placenta
Umbilical arteries
How many :
Umbilical veins?
Umbilical arteries ?
1
2
The nature _____ supports gas, nutrient and waste exchange between fetal and maternal blood
Placenta
Outside of the amnion is the _____; which has moth and follows surfaces
Chorionic membrane
The chorionic membrane has many many villi clusters called _____
Cotyledons
______ of the placenta provide a massive surface area for metabolic exchange
Chorionic villi
Chorionic villi are efficient for ____
Metabolic exchange
What structure is important for anchoring the placenta to the uterine lining
Chorionic villi
What is exchanged at the placenta ?
Waste removal
Oxygen in CO2 out
Nutrient delivery
Functions of the placenta (non exchange)
Hormone production
Anchorage
Immunity
This hormone stimulates growth of the myometrium increasing uterine strength for parturition , helps prepare mammary glands for lactation
Estrogen
This hormone suppresses uterine contraction to provide quiet environment for fetus
Progesterone
this hormone maintains the corpus luteum of pregnancy , stimulates secretion of testosterone by developing testes in XY embryos
HCG
This hormone softens cervix in preparation for cervical dilation at parturition
Relaxin
The placenta produces ____ directly and ___ indirectly from the fetal androgens (DHEA)
Progesterone Estrogen
The placenta itself can convert _____ into progesterone but lacks some of the enzymes necessary to convert that into estrogen
Cholesterol
The placenta can convert ___ derived from cholesterol in fetal adrenal cortex not estrogen when it reaches the placenta by means of fetal blood
DHEA
High concentration of ____ and ____ maintain pregnancy and support fetus
Estrogen and progesterone
_______
- stimulates growth of the myometrium, the muscular layer of the uterus that will contract to deliver the fetus
- promotes duct development in the breasts to support lactation after baby is born
Estrogen
_______
- prevents premature myometrium, contraction
- promotes mucous plug at cervix to exclude contaminants
- stimulates development of the milk producing glands of breast
Progesterone
Maternal changes with pregnancy :
_____ enlargement coordinated with fetal growth
Uterine
Maternal changes with pregnancy :
Breast prepare for milk production ; ___ and ____ growth
Duct and gland
Maternal changes with pregnancy :
Blood ____ increased by 30% while blood ____ is reduced
Volume
Pressure
Maternal changes with pregnancy :
respiratory activity ____ by 20%
Increased
Maternal changes with pregnancy :
___ outout increases to manage excretion of maternal/fetal wastes
Urine
Maternal changes with pregnancy :
Metabolic changes to shunt ____ and ___ to developing fetus
Glucose and fatty acids
______= the process of delivering a baby and the placenta
Parturition
The body prepares for parturition in the late stages of _____
Gestation
What happens for the body to prepare for parturition in late stages of gestation ?(3)
- milked contractions
-relaxin for cervix to soften - fetus shifts down
Prior to birth the baby drops towards the cervix (also called _____)
Lightening
_____________= myometrium responsiveness (contractions and greater number of oxytocin receptors) along with cervical softening
Coordinated fetal preparedness
_______ = high CRH , high estrogen, inflammatory response
Onset Triggers
_______ for precession to delivery= uterine contractions leading to cervical stretch and increased oxytocin secretion plus prostaglandin secretion
Positive feedback
Describe coordinated fetal preparedness for parturition
Contractions and increase number of oxytocin receptors and cervical softening
Describe onset triggers for parturition
High CRH and estrogen
Inflammatory response
Describe positive feedback look for progression to delivery
Uterine contractions = cervical stretch = increased oxytocin +prostaglandin secretion
What happens to estrogen and progesterone when delivery of baby occurs ?
Both concentrations decline rapidly
What are The 3 stages of labour
- Cervical dilation
- Delivery of baby
- Delivery of placenta
Over several weeks following birth the uterus will shrink to pre-pregnancy size, a process called ______
Uterine involution
Why does uterine involution take place ?
Estrogen and progesterone drop rapidly
What causes certain mothers over others to have a more rapid involution process and why
Breast feed ; oxytocin release helps contract myometrium,
Mother that breastfeed have a more rapid _____ process since ____ release through breastfeeding cycles help contract the myometrium
Involution
Oxytocin
Average Canadian rate of pre term birth is __ %
8
____ twins are always the same genetic sex
Identical
_____ twins can be the same genetic sex or different
Fraternal
Dizygotic twinning is the same as ____ twinning
Fraternal
Monozygotic twinning is the same as _____ twinning
Identical
2 oocytes fertilized by 2 spermatozoa and the 2 blastocysts implant separately, each fetus has its own amnion and chorion (placenta) this is known as ______
Fraternal twinning
_____ twinning can occur by early, middle, late or very late embryo division
Monozygotic
Monozygotic twinning when 2 blastocysts implant (dichorionic/diamiotic membranes ) is known as _____ embryo division
Early
Monozygotic twinning when 1 pre-implantation blastocyst and 2 ICM’s implant (monochorionic/diamiotic membranes ) is known as _____ embryo division
Middle
Monozygotic twinning when post-implantation split of ICM implant (monochorionic/monoamiotic membranes ) is known as _____ embryo division
Late
Monozygotic twinning when ICM’s may not split (monochorionic/monoamiotic membranes ) produces _____
Conjoined twins