Thiazide Diuretics Flashcards

1
Q

Drugs in the class Thiazide Diuretics

A

Bendroflumethiazide

Indapamide

Chlortallidone

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2
Q

Indications of Thiazide Diuretics

A

Alternative 1st line for HTN when CCB contraindicated

Or add on for HTN when not controlled by CCB +ACE/ARB

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3
Q

MOD of Thiazide Diuretics

A

Inhibit Na/Cl cotransporter in the distal convulted tubules of the nephron

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4
Q

SE of Thiazide Diuretics

A

Hyponatremia - because of preventing Na reabsorption

Hypokalaemia –> arrythmias

May cause impotence

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5
Q

Warnings of Thiazide Diuretics

A

avoid in pts with hypokalaemia

Hyponatreamia

gout - may precipitate attacks

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6
Q

Interactions of Thiazide Diuretics

A

NSAIDs reduce effect - although low aspirin is ok

other drugs lowering potassium (loop) is best avoided

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