Thiazide Diuretics Flashcards
1
Q
Drugs in the class Thiazide Diuretics
A
Bendroflumethiazide
Indapamide
Chlortallidone
2
Q
Indications of Thiazide Diuretics
A
Alternative 1st line for HTN when CCB contraindicated
Or add on for HTN when not controlled by CCB +ACE/ARB
3
Q
MOD of Thiazide Diuretics
A
Inhibit Na/Cl cotransporter in the distal convulted tubules of the nephron
4
Q
SE of Thiazide Diuretics
A
Hyponatremia - because of preventing Na reabsorption
Hypokalaemia –> arrythmias
May cause impotence
5
Q
Warnings of Thiazide Diuretics
A
avoid in pts with hypokalaemia
Hyponatreamia
gout - may precipitate attacks
6
Q
Interactions of Thiazide Diuretics
A
NSAIDs reduce effect - although low aspirin is ok
other drugs lowering potassium (loop) is best avoided