Nitrofurantoin Flashcards
1
Q
Indications of Nitrofurantoin
A
First line for uncomplicated UTI - alternatives trimethoprim, amoxicillin
2
Q
Nitrofurantoin mechanism of action
A
It is metabolised inside bacterial cells.
Its active metabolites damage the DNA, causing cell death (Bactericidal).
3
Q
Side effects of Nitrofurantoin
A
Allergy
GI upset (nausea and diarrohoea)
Dark yellow or brown urine
Hepatitis
Peripheral neuropathy
Haemolytic anaemia
4
Q
Warnings of Nitrofurantoin
A
pregnant woman towards term
babies in the first 3 months of life
Renal impairment
5
Q
Interactions of Nitrofurantoin
A
Non
