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Drugs - third year > Misc > Flashcards

Misc Flashcards

1
Q

Drugs with no interactions

A

Anticholinergics - antimuscuranics

Nitrofurantoin

Oxygen

5a reductase inhibitors

Laxatives - stimulant

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2
Q

Never combine

A

Methotroxate (DMARD) with Trimethoprim (ABx)

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3
Q

Drugs which are under penicillin allergy

A

Tazobactam/tazocin

Penicillins

Cephalosporins (Cefradine) and carbapanems

Co-amoxiclav

Augmentin

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4
Q

Aminoglycosides interactions

A

Cephalosporins (Cefradine)

Loop diuretics increase risk of ototoxicity and nephrotoxicity

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5
Q

risk of cdiff

A

Quinolones

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6
Q

Drugs that prolong QT interval or cause arrythmias

A

Macrolides

Quinolones

antiarrythmiacs

amitriptyline

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7
Q

drugs causing ototoxicity

A

Aminoglycosides

vancomycin

risk increases with diuretics if mixed with either of above

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8
Q

Avoid aspirin in

A

nasal polyps

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9
Q

Dont use these drugs in asthmatics

A

Beta blockers

adenosine - antiarrythmatic

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10
Q

Tricyclic antidepressants overdose

A

dilated pupils

ECG - broad complex tachycardia

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11
Q

Atropine

A

An antimuscuranic given IV usually to increase heart rate

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12
Q

Beta blockers side effect

A

Causes erectile impotence

lethargy drowsiness

hypotension

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13
Q

diuretics

A

abuse of diuretics results in metabolic alkalosis

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14
Q

drugs causing Hyperkalaemia

A

ACE inhibitors or angiotensin II receptor blockers

spironolactone
heparin

ciclosporin

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15
Q

ACE side effects

A

hyperkalaemia

angioedema

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16
Q

calcium channel blockers side effects

A

Headache - amlodopine

verapamil - heart block, bradycardia

Diltiazem - ankle swelling

17
Q

Amiodarone SE

A

peripheral neuropathy

18
Q

Digoxin SE

A

bradycardia

If toxicity will cause - N/V diarrhoea, and disturbances of color vision “yellow haze”

Gynaecomastia

19
Q

drugs causing Gynaecomastia

A

spironolactone
digoxin
antipsychotics

20
Q

digoxin SE

A

Gynaecomastia

21
Q

causes of Peaked T waves

A

hyperkalaemia

myocardial ischaemia

22
Q

Inverted T waves

A 
myocardial ischaemia
digoxin toxicity
subarachnoid haemorrhage
arrhythmogenic right ventricular cardiomyopathy
pulmonary embolism ('S1Q3T3')
Brugada syndrome
23
Q

Asthma contraindications

A

Beta blockers

adenosine

24
Q

amiodarone SE

A

Slate-grey

hypothyroidism

25
Q

Thiazides SE

A

hypercalcaemia

impotence

hypoK/Na

Gout

26
Q

sulfonylureas SE

A

hypoglycaemia, weight gain and hyponatraemia

27
Q

metformin MOA

A

decreases hepatic gluconeogynesis

increases insulin sensitivity

28
Q

Taking quinolones and NSAIDs

A

increased risk of seizures

29
Q

Taking quinolones and preinisolone

A

increased risk of tendon rupture

30
Q

Aminoglycosides SE

A

Nephrotoxicity - increase w/ vanc, ceph, ciclosporine

ototoxicity

31
Q

amlodopine vs amitriptilyne

A

amlodopine is a CCB

amitriptilyne is a tricyclic anti depressant

32
Q

Amoxicillin

A

causes erythema nodosum – shin lesion

33
Q

first trimester avoid

A

sodium valproate

warfarin

trimethoprim - tetrogenic

34
Q

Later stages of pregnancy avoid

A

warfarin

nitrofurantoin

35
Q

avoided in pregnancy

A

aldosterone antagonists

carbamazepine caution only and sp r/v

tetracyclines and children under 12

36
Q

Antifungal durgs

A

nystatin

flucanazole

37
Q

third trimester avoid

A

Aspirin

38
Q

Drugs causing pulmonary fibrosis

A

Amiodarone

Nitrofurantoin

methotroxate

Sulfasalazine

Drugs - third year (28 decks)

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