Misc

Question 1

Drugs with no interactions

Answer 1

Anticholinergics - antimuscuranics

Nitrofurantoin

Oxygen

5a reductase inhibitors

Laxatives - stimulant

Question 2

Never combine

Answer 2

Methotroxate (DMARD) with Trimethoprim (ABx)

Question 3

Drugs which are under penicillin allergy

Answer 3

Tazobactam/tazocin

Penicillins

Cephalosporins (Cefradine) and carbapanems

Co-amoxiclav

Augmentin

Question 4

Aminoglycosides interactions

Answer 4

Cephalosporins (Cefradine)

Loop diuretics increase risk of ototoxicity and nephrotoxicity

Question 5

risk of cdiff

Answer 5

Quinolones

Question 6

Drugs that prolong QT interval or cause arrythmias

Answer 6

Macrolides

Quinolones

antiarrythmiacs

amitriptyline

Question 7

drugs causing ototoxicity

Answer 7

Aminoglycosides

vancomycin

risk increases with diuretics if mixed with either of above

Question 8

Avoid aspirin in

Answer 8

nasal polyps

Question 9

Dont use these drugs in asthmatics

Answer 9

Beta blockers

adenosine - antiarrythmatic

Question 10

Tricyclic antidepressants overdose

Answer 10

dilated pupils

ECG - broad complex tachycardia

Question 11

Atropine

Answer 11

An antimuscuranic given IV usually to increase heart rate

Question 12

Beta blockers side effect

Answer 12

Causes erectile impotence

lethargy drowsiness

hypotension

Question 13

diuretics

Answer 13

abuse of diuretics results in metabolic alkalosis

Question 14

drugs causing Hyperkalaemia

Answer 14

ACE inhibitors or angiotensin II receptor blockers

spironolactone
heparin

ciclosporin

Question 15

ACE side effects

Answer 15

hyperkalaemia

angioedema

Question 16

calcium channel blockers side effects

Answer 16

Headache - amlodopine

verapamil - heart block, bradycardia

Diltiazem - ankle swelling

Question 17

Amiodarone SE

Answer 17

peripheral neuropathy

Question 18

Digoxin SE

Answer 18

bradycardia

If toxicity will cause - N/V diarrhoea, and disturbances of color vision “yellow haze”

Gynaecomastia

Question 19

drugs causing Gynaecomastia

Answer 19

spironolactone
digoxin
antipsychotics

Question 20

digoxin SE

Answer 20

Gynaecomastia

Question 21

causes of Peaked T waves

Answer 21

hyperkalaemia

myocardial ischaemia

Question 22

Inverted T waves

Answer 22

myocardial ischaemia
digoxin toxicity
subarachnoid haemorrhage
arrhythmogenic right ventricular cardiomyopathy
pulmonary embolism ('S1Q3T3')
Brugada syndrome

Question 23

Asthma contraindications

Answer 23

Beta blockers

adenosine

Question 24

amiodarone SE

Answer 24

Slate-grey

hypothyroidism

Question 25

Thiazides SE

Answer 25

hypercalcaemia

impotence

hypoK/Na

Gout

Question 26

sulfonylureas SE

Answer 26

hypoglycaemia, weight gain and hyponatraemia

Question 27

metformin MOA

Answer 27

decreases hepatic gluconeogynesis

increases insulin sensitivity

Question 28

Taking quinolones and NSAIDs

Answer 28

increased risk of seizures

Question 29

Taking quinolones and preinisolone

Answer 29

increased risk of tendon rupture

Question 30

Aminoglycosides SE

Answer 30

Nephrotoxicity - increase w/ vanc, ceph, ciclosporine

ototoxicity

Question 31

amlodopine vs amitriptilyne

Answer 31

amlodopine is a CCB

amitriptilyne is a tricyclic anti depressant

Question 32

Amoxicillin

Answer 32

causes erythema nodosum – shin lesion

Question 33

first trimester avoid

Answer 33

sodium valproate

warfarin

trimethoprim - tetrogenic

Question 34

Later stages of pregnancy avoid

Answer 34

warfarin

nitrofurantoin

Question 35

avoided in pregnancy

Answer 35

aldosterone antagonists

carbamazepine caution only and sp r/v

tetracyclines and children under 12

Question 36

Antifungal durgs

Answer 36

nystatin

flucanazole

Question 37

third trimester avoid

Answer 37

Aspirin

Question 38

Drugs causing pulmonary fibrosis

Answer 38

Amiodarone

Nitrofurantoin

methotroxate

Sulfasalazine