Thalidomide Flashcards
1
Q
Class
A
Teratogen
2
Q
Action
A
Inhibits growth factors
for the proliferation of
multiple myeloma
3
Q
Mechanism of Action
A
Activates apoptotic pathways. Its teratogenic properties come from inhibition of promoter regions of the genes that develop limbs
4
Q
Clinical Use
A
Multiple myeloma
5
Q
Adverse effects
A
Vomiting Dry mouth Dyspepsia Constipation Bradycardia Cardiac failure DVT
6
Q
what type of agent is Thalidomide?
A
is an immunomodulatory agent
7
Q
what other effect does thalidomide have?
A
have anti-angiogenic effects
