Temperature Regulation

Question 1

the area of the brain that regulates body temperature

Answer 1

hypothalamus

Question 2

Temperature sensors are located in the ___ and ____

Answer 2

skin and hypothalamus

Question 3

If the detected temp < set point temp the body will ___ heat

Answer 3

generate

Question 4

if the detected temp > set point temp the body will activate heat ____ mechanism

Answer 4

heat loss

Question 5

the most potent heat generating mechanism

Answer 5

shivering

Question 6

Cite examples of heat generating mechanism

Answer 6

shivering, thyroid hormone, decreased sweating, piloerection, skin vasoconstriction (alpha 1), brown fat (beta 3)

Question 7

receptors that are found in brown fat

Answer 7

beta 3

Question 8

receptors for skin vasoconstriction

Answer 8

alpha 1

Question 9

the most potent heat loss mechanism

Answer 9

radiation

Question 10

cite examples of heat loss mechanisms

Answer 10

radiation, convection, sweating, skin vasodilation, decreased heat production

Question 11

part of the hypothalamus that plays a role for heat loss

Answer 11

anterior hypothalamus

Question 12

part of the hypothalamus that plays a role for heat gain

Answer 12

posterior hypothalamus

Question 13

pyrogens initiate fever by ___ in the hypothalamus

Answer 13

increasing the set point temperature in hypothalamus

Question 14

cytokine implicated in fever

Answer 14

IL1

Question 15

the increase in this prostaglandin increases the set point temperature in hypothalamus

Answer 15

PGE2

Question 16

irreversible of COX that decreases PGE2

Answer 16

aspirin

Question 17

this inhibits the release of arachidonic acid from brain

Answer 17

steroid

Question 18

[diagnose]

excessive sweating that decreases BP and causes syncope

Answer 18

heat exhaustion

Question 19

[diagnose]

high body temperature causing tissue damage

impaired sweating

Answer 19

heat stroke

Question 20

[diagnose]

ambient temperature is low, core temp cannot be maintained at set point

Answer 20

hypothermia

Question 21

[diagnose]

overexcitation of skeletal muscle that results in excess Ca release from SR due to halothane and succinylcholine

Answer 21

malignant hypertension