Sympathetic Agonist Drugs (Sympathomimetics) Flashcards

1
Q

isoproterenol

A

B1 and B2 agonist

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2
Q

DA at low doses

A

D1 and D2 agonist

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3
Q

DA at medium doses

A

B1 and B2 agonist

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4
Q

DA at high doses

A

A1 and A2 agonist

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5
Q

Dobutamine

A

B1 > B2 agonist

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6
Q

indications for dobutamine

A

used in stress tests and sometimes in heart failure–> increases HR and contractility

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7
Q

Phenylephrine

A

A1 selective agonist

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8
Q

phenylephrine uses

A

pupilary dilation and nasal decongestion

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9
Q

albuterol, levalbuterol, salmeterol

A

B2 > B1 agonist

used for asthma

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10
Q

Advantage of levalbuterol over albuterol and salmaterol

A

less tachycardia (more B2 specific)

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11
Q

terbutaline

A

B2 > B1 agonist

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12
Q

main use of terbutaline

A

tocolysis–> inhibits uterine contraction

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13
Q

Clonidine

A

A2 agonist–> decreses NE release; used for HTN

*issues with rebound hypertension

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14
Q

alpha-methyldopa; main use

A

A2 agonist–> used in pregnancy-induced HTN, like pre-eclampsia

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15
Q

3 indirect sympathetic agonist

A
  1. amphetamines
  2. Ephedrine
  3. cocaine
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16
Q

amphetamine and ephedrine MOA

A

release stored catecholamines

17
Q

cocaine MOA

A

inhibits catecholamine reuptake

18
Q

given in nebulizer for asthma

A

albuterol or levalbuterol

19
Q

DOC for anaphylaxis

A

Epinephrine

20
Q

MC first line agent for septic shock or cardiogenic shock

A

NE

21
Q

NE

A

A1, A2, B1 agonist

22
Q

Epinephrine

A

A1, A2, B1, B2 agonist

23
Q

given subQ for asthma, etc

A

terbutaline–> remember, also mainly used for tocolysis, also given subQ for this = rapid onset

24
Q

used by ENT to constrict nasal vessels

A

Phenylephrine, sometimes cocaine

25
Q

Ritrodine

A

B2 selective agonist–> can be used to reduce premature uterine contractions

26
Q

advantage of using clonidine or alpha methyldopa for HTN

A

HTN with kidney dz–> decrease hypertension with no decrease in blood flow to kidney