Sympathetic Agonist Drugs (Sympathomimetics) Flashcards
isoproterenol
B1 and B2 agonist
DA at low doses
D1 and D2 agonist
DA at medium doses
B1 and B2 agonist
DA at high doses
A1 and A2 agonist
Dobutamine
B1 > B2 agonist
indications for dobutamine
used in stress tests and sometimes in heart failure–> increases HR and contractility
Phenylephrine
A1 selective agonist
phenylephrine uses
pupilary dilation and nasal decongestion
albuterol, levalbuterol, salmeterol
B2 > B1 agonist
used for asthma
Advantage of levalbuterol over albuterol and salmaterol
less tachycardia (more B2 specific)
terbutaline
B2 > B1 agonist
main use of terbutaline
tocolysis–> inhibits uterine contraction
Clonidine
A2 agonist–> decreses NE release; used for HTN
*issues with rebound hypertension
alpha-methyldopa; main use
A2 agonist–> used in pregnancy-induced HTN, like pre-eclampsia
3 indirect sympathetic agonist
- amphetamines
- Ephedrine
- cocaine