Seizure and Seizure Drugs Flashcards

1
Q

partial seizure

A

affects one part of brain (gen. temporal)

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2
Q

simple seizure

A

pt. maintains conciousness

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3
Q

generalized seizure

A

spreads to affect more than one part of brain

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4
Q

complex seizure

A

pt loses conciousness

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5
Q

staring, quivering of lips or smacking lips

A

absence (petit-mal) generalized seizure

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6
Q

twitching seizure

A

Myoclonic, generalized

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7
Q

muscles get stiff, then starts twitching

A

Tonic-clonic (grand-mal)

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8
Q

gets stiff only

A

tonic

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9
Q

loses muscle tone and just falls to floor

A

atonic

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10
Q

What is status epilepticus (2)

A
  1. complex seizure lasting more than 5 mins OR

2. multiple seizures w/o regaining conciousness in between

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11
Q

tx for status epilepticus

A

IV lorazepam (or diazepam)

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12
Q

DOC for absence seizures

A

ethosuxamide

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13
Q
  • 7 side effects of phenytoin
A
  1. gingival hyperplasia
  2. hirsutism
  3. fetal hyantoin syndrome (cleft lip and palate, heart defects, mental retardation)
  4. megaloblastic anemia
  5. peripheral neuropathies
  6. drug-induced lupus
  7. Stevens-johnson syndrome
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14
Q

5 anti-convulsants that cause stevens-johnson (and 3 other that do too)

A
  1. ethosuxamide
  2. lamotrigine
  3. carbamazepine
  4. phenytoin
  5. phenobarbitol
  6. Sulfonamides
  7. penicillins
  8. allopurinol
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15
Q

3 drugs used to treat tonic-clonic (grand mal) seizures

A
  1. valproic acid (supposed to be best for generalized)
  2. carbamazepine
  3. phenytoin
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16
Q

best drug for partial seizure

A

lamotrigine

17
Q

5 drugs that cause agranulocytosis

A
  1. Carbemazepine
  2. Clazopine
  3. Colchicine
  4. Propylthiouracil (PTU)
  5. Methimazole
18
Q

6 drugs that induce CYPs (“coronas, guiness, and PBR induce chronic alcoholism”)

A
  1. carbamazepine
  2. griseofulvin
  3. phenytoin
  4. barbituates
  5. rifampin
  6. St. Johns Wort
    Also chronic alcoholism (EtOH)