NTs-> site of synthesis and alteration in disease Flashcards

1
Q

locus ceruleus

A

NE

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2
Q

Ventral tegmentum and SNc (midbrain)

A

Dopamine

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3
Q

Raphe nucleus (pons)

A

Serotonin

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4
Q

Basal nucleus of Meynert

A

ACh

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5
Q

Nucleus accumbens

A

GABA (needs B6)

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6
Q

nucleus involves in stress and panic

A

locus ceruleus

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7
Q

reward center, pleasure, addiction, fear

A

nucleus accumbens (and septal nucleus)

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8
Q

what 3 NT decreased in depression

A
  1. NE
  2. Dopamine
  3. Serotonin
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9
Q

What two NT increased in anxiety? which is elevated

A
  1. serotonin and GABA decreased

1. NE is increased

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10
Q

increased in Schizophrenia

A

Dopamine

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11
Q

what 2 decreased in Huntingtons

A
  1. ACh

2. GABA

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12
Q

decreased in Alzheimer

A

ACh

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13
Q

decreased in Parkinsons

A

Dopamine

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14
Q

increased in REM sleep

A

ACh

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