Cytokine Functions

Question 1

2 secreted by Th1 cells

Answer 1

1. IL-2–> stimulate growth of helper, cytotoxic, and Treg

2. INF - gamma–> activates macrophages and suppresses Th2 development

Question 2

3 secreted by Th2 cells

Answer 2

1. IL-2–> growth of helper, cytotox and Treg cells
2. IL-4–> stim B cells and increases Th2 proliferation
3. IL-10–> inhibits macrophages and inhibits TH1 diff.

Question 3

Stimulates Th1 production

Answer 3

Il-12 –> secreted by macrophages and B cells

Question 4

inhibits Th1 diff

Answer 4

IL-10

Question 5

stimulates Th2 production

Answer 5

IL-4

Question 6

inhibits Th2 production

Answer 6

INF-gamma

Question 7

function of Th1

Answer 7

stimulate macrophages and cytotoxic T cells

Question 8

function of Th2

Answer 8

stimulate plasma cells to make Ab

Question 9

stimulate NK cells (4(

Answer 9

1. IL-12
2. IL-2
3. INF alpha
4. INF- beta

Question 10

released by NK cells

Answer 10

INF gamma

Question 11

2 produced by Treg cells

Answer 11

1. IL-10

2. TGF-beta