Autoantibodies ( 4 stars!!) Flashcards by Zach Smalley

Q

Anti-IgG IgM Abs

A

Rheumtoid arthritis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-citrullinated protein Abs (APCA)

A

Rheumatoid arthritis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Which RA Ab is more specific

A

ACPA

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-centromere Abs

A

CREST

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-DNA topoisomerase

A

diffuse scleroderma (also called anti-scl-70)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-histone

A

Drug induced lupus

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Antinuclear antibodies (ANA)

A

SLE

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-Smith

A

SLE

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

which SLE Ab is most specific

A

Anti-Smith–> ANA is a screen

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-ds DNA

A

Lupus nephritis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-Jo-1

A

Polymyositis/Dermatomyositis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-Ro

A

Sjogrens syndrome (also called Anti-SSA)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-La

A

Sjogrens syndrome (also called anti-SSB)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-U1-RNP

A

mixed connective tissue disease

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

anti-desmoglein

A

Pemphigus vulgaris

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Anti-acetylcholine receptor

A

Myasthenia gravis

Q

Anti-endomysial (anti-tissue transglutamase)

A

Celiac disease

Q

Anti-gliadin

A

Celiac disease

Q

Anti-mitochondrial

A

Primary Biliary cirrhosis

Q

Anti-smooth muscle

A

autoimmune hepatitis

Q

Anti-glutamate decarboxylase

A

type I Diabetes

Q

Anti-thyrotropin receptor

A

Graves disease

Q

Anti-thyroid peroxidase

A

Hashimoto thyroiditis (also called anti-TPO)

Q

Anti-thyroglobulin

A

Hashimoto or Graves

Q

Anti-basement membrane

A

Goodpasture’s Syndrome

Q

c-ANCA

A

Granulomtosis w/ polyangitis (Wegner’s)

*this and Goodpastures affect lung and kidney

Q

p-ANCA (3)

A

Pauci-immune crescenteric glomerulonephritis
Churg-strauss syndrome
Microscopic polyangiitis