Sveppalyf Flashcards

1
Q

Amphotericin

  • virkni
  • hvaða sveppir
  • aukav
A
  • gerir göt á frumuhimnu (sækni í ergosterol)
  • candida, aspergillus, cryptococcus
  • nýrnaskemmdir, hypoK/Mg, beinmergur

bara gefið i.v.

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2
Q

Nystatin

A

bindst sterólum og breytir gegndræpi

mycostatin mixtúra
=> candida sýk í slímhúðum munns og vélinda

ATH FRÁSOGAST EKKI!

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3
Q

Caspofungin

  • verkun
  • hvaða sveppir
A

echinocandins
hamla myndun veggs með því að hindra 1,3-beta glucan synthase
gegn aspergillus og candida
gefið i.v.

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4
Q

Azole lyf

A

hamla lanosine 14 alpha demethylase og veggurinn verður aflagaður

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5
Q

dæmi um Azole

A

katoconazole p.os
flucanozole MTK
itraconazole
miconazole 3x/dag. lungu

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6
Q

Terbinafine

A

hamlar squalene epoxidase

-safnast upp í fituvef

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7
Q

lyf sem hamlar squalene epoxídasa

A

Terbinafine

-húðsýkingar

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8
Q

lyfa sem hindrar glucan synthase

A

caspofungin

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9
Q

lyf sem breyta gegndræpi

A

nystatin

amphotericin

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10
Q

Náttúruleg sveppalyf

A

amphotericin
nystatin
caspofungin

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11
Q

synthetic sveppalyf

A

azole lyf

terbinafine

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