ónæmisbælandi lyf Flashcards by helga run gardarsdottir | Brainscape

Q

cyclosporin

A

bindst við cyclophilin og hamlar þá calcineurin

-hindrar myndun IL-2,IL-3 og TNF-gamma

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Q

mesalazin

A

5-aminosalysylic acid

-bólgusjúkdómur í þörmum

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Q

Basiliximab

A

mótefni gegn IL-2 viðtökum

strax eftir líffæraígræðslur

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Q

Sulfazalasine

A

sulfasalazine + 5-ASA

+aukaverkanir agranulocytosis og hypospermia

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Q

mycophenylate

A

hindrar inosine monophosphate dehydrogenasa

-hindrar myndun púrína

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Q

Azatioprine

A

–> 6-mercaptoopurine

- hindrar myndun púrína

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Q

Sirolimus

A

hamlar áhrifum IL-2 á eitilfrumur

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Q

Tacrolimus

A

hindrar calineurin

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Q

Everolimus

A

hindrar áhrif IL-2 á eitilfrumur

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Q

Hydrochloroquine

A

minnkar virkni TLR-9

-dendritic frumur presentera ekki

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Q

Leflunomide

A

hindra dihydrooroate dehydrogenasa

-hamla myndun pyrimidina

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Q

cyclophosphamide er notað í

A

scleroderma

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Q

Penicillamine

A

minnka myndun IL-1 og collagen

-RA, heavy metal eitrun, Willsons disease

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Q

hvaða lyf minnka endurupptöku þvagsýru

A

probenecid

sulfynpyrazone

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Q

Cochicine

A

hamlar fjölliðun beta-tubulin í microtubules

-hindrar neutrophila

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Q

þvagsýrukast

A

NSAIDs
Sterar
Colchicine

Q

fyrirbyggjandi við þvagsýrukasti

A

Coclicine
Probenecid
Sulfynpyrazone
Allopurinol

Q

Allopurinol

A

xanthine oxidasi breysti í alloxanthine sem hamlar ensímið og því eykst xanthine og hypoxanthine