Succinylcholine G6

Question 1

Succinylcholine Class

Answer 1

• Depolarizing neuromuscular blocker
• Skeletal muscle relaxant

Question 2

Succinylcholine MOA

Answer 2

• Ultra-short-acting depolarizing skeletal muscle relaxant that mimics acetylcholine
• Binds with cholinergic receptors on motor endplate, producing phase I block manifested by muscle fasciculations

Question 3

Succinylcholine Indications

Answer 3

• Adjunct to provide skeletal muscle relaxation and facilitate tracheal intubation and ventilation

Question 4

Succinylcholine Adult dose

Answer 4

• 1 – 1.5 mg/kg IV/IO rapid push

Question 5

Succinylcholine Contraindications

Answer 5

• Known hypersensitivity
• Renal failure
• Para or quadriplegic, muscular dystrophy history or other neuromuscular diseases
• Stroke with residual muscle dysfunction
• History of malignant hyperthermia
• Penetrating ocular injuries due to increased intraocular pressure caused by med
• Pt sustained multisystem trauma, burns, prolonged immobilization, or limb entrapment resulting in hyperkalemia
• Known or suspected hyperkalemia
• Predicted difficult intubation

Question 6

Succinylcholine Adverse effects

Answer 6

• Apnea
• Respiratory depression
• Dysrhythmias,
• Cardiac arrest
• Hyperkalemia (trauma and burn patients)
• Increased intracranial, intraocular and intragastric pressures
• Excessive salivation
• Prolonged muscle rigidity
• Rhabdomyolysis
• Malignant hyperthermia

Question 7

Succinylcholine Pediatric dose

Answer 7

• Pediatrics: 1 – 1.5 mg/kg IV/IO rapid push
• Infants: 2 mg/kg IV/IO rapid push