Nirtro G1

Question 1

Nitro Class

Answer 1

• Nitrate vasodilator
• Antianginal

Question 2

Nitro MOA

Answer 2

• Smooth muscle relaxant acting on vascular, uterine, bronchial, and intestinal smooth muscle.
• Decreases preload – increases workload of heart’s right-side by causing blood pooling in lower extremities.
• Decreases afterload – arterial vasodilation reduces vascular resistance and decreases myocardial oxygen demand.
• Coronary artery vasodilation increases blood flow to myocardium.

Question 3

Nitro Indications

Answer 3

• Ischemic cardiac chest pain (Angina or MI)
• Congestive heart failure with pulmonary edema

Question 4

Nitro Adult dose

Answer 4

• 0.4 mg SL tablet/spray, may repeat every 3-5 minutes up to 3 doses if systolic BP is greater than 90 mmHg

Question 5

Nitro Contraindications

Answer 5

• Known hypersensitivity
• Hypotension (SBP < 90 mmHg)
• Hypovolemia
• Use of erectile dysfunction (ED) drugs in the last 24 hours.
• Suspected head bleed or increased intracranial pressure (ICP)

Question 6

Nitro Adverse reactions

Answer 6

• Cardiovascular: hypotension, reflex tachycardia, bradycardia
• Neurological: Headache, dizziness, syncope

Question 7

Nitro Pediatric dose

Answer 7

• None