Norepinephrine G4 Flashcards

1
Q

Norepinephrine Class

A

• Sympathomimetic

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2
Q

Norepinephrine MOA

A

• Alpha-adrenergic response
o Vasoconstriction

• Beta1-adrenergic responses
o Increases the heart rate
o Increases myocardial contractility

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3
Q

Norepinephrine Indication

A

• Severe hypotension refractory to IV boluses caused by
o Cariogenic shock
o Septic shock
o Neurogenic shock

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4
Q

Norepinephrine Adult dose

A

• Infusion:
0.1 to 2.0 mcg/kg/minute, titrated to effect

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5
Q

Norepinephrine Contraindications

A

• Hypotension caused by hypovolemia

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6
Q

Norepinephrine Adverse effects

A

• Extravasation of the IV/IO may cause tissue necrosis
• Tachycardia
• Increased myocardial oxygen demand
• Hypertension
• Dysrhythmias

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7
Q

Norepinephrine Pediatric dose

A

• Infusion:
0.05 to 0.1 mcg/kg/minute, titrated to effect

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