Atropine Sulfate G4

Question 1

Atropine Class

Answer 1

• Anticholinergic
• Parasympathetic blocker
• Antidote

Question 2

Atropine MOA

Answer 2

• Blocks the action of acetylcholine
• Increases the heart rate
• Reverses the symptoms of cholinergic poisoning

Question 3

Atropine Indications

Answer 3

• Hemodynamically significant bradycardia
• Organophosphate poisoning
• Carbamate poisoning
• Nerve agent exposure

Question 4

Atropine Adult dose

Answer 4

• Hemodynamically significant bradycardia:
1.0 mg may repeat the dosage every 3 to 5 minutes to maximum dosage 3.0 mg

• Organophosphate poisoning/carbamate poisoning/nerve agent exposure:
1.0 to 4.0 mg May double the dosage every 5 minutes

• ET: 2.0 to 2.5 mg diluted in 10 mL normal saline

Question 5

Atropine Contraindications

Answer 5

• Known hypersensitivity to the drug
• Tachycardia
• Hypothermia-induced hemodynamically significant bradycardia

Question 6

Atropine Adverse effects

Answer 6

• Tachycardia
• Palpitations
• Flushed, hot, dry skin
• Dizziness

Question 7

Atropine Pediatric dose

Answer 7

• Hemodynamically significant bradycardia:
0.02 mg/kg may repeat the dosage every 3 to 5 minutes to maximum dosage 1.0 mg in children and 2.0 mg in adolescents

• Organophosphate poisoning/carbamate poisoning/nerve agent exposure:
0.03 to 0.05 mg/kg every 10 to 20 minutes