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Parasitology Lec > Strongyloides Stercolaris > Flashcards

Strongyloides Stercolaris Flashcards

1
Q

Common name:
SS

A

● Threadworm
● Cochin-China Diarrhea ○ Cochin-China → Vietnam

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2
Q

Facultative parasite

● (rhabditiform)

● (filariform female)

A

Free-living form

Parasitic form

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3
Q

MALE SS

● Smaller the female measuring 0.7mm x 0.04mm

● Ventrally____ tail,___ copulatory spicules, a____, no_____

● Parasitic males are not reliably identified

A

curved/ two/ gubernaculum/ caudal alae

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4
Q

Female parasitic SS

● what color? with a finely striated cuticle, measuring 2.2mm x 0.04mm

● Reproduction:____

● Anterior:
○ Slender, tapering

● Posterior:
○ Short, conical, pointed tail

● Short buccal cavity with____ indistinct lips

● Long, slender esophagus extending to the anterior fourth of the body

● Intestine is continuous to the subterminal anus

● Vulva at one-third the length of the body from posterior end

● Uteri contain single file of 9-12 ova

A

Colorless, semi-transparent

Parthenogenesis

4

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5
Q

Free living female SS

● Reproduction:_____

● Smaller than parasitic female measuring 1mm x 0.06mm

● Muscular double-bulbed esophagus

● Intestine is straight cylindrical tube

A

Oviparous

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6
Q

Phasmid/ Aphasmid?

A

Phasmid

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7
Q

Hosts SS

A

Humans/ monkey

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8
Q

MOT SS

A

Skin penetration

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9
Q

Infective stage SS

A

L3

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10
Q

Diagnostic stage SS

A

Rhabditiform

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11
Q

Diagnosis SS

A

● DFS

● Concentration techniques (FECT)

● Baermann Funnel Gauze method

● Harada-Mori culture

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12
Q

Treatment SS

A
  1. Albendazole
  2. Pipperazine citrate
  3. Mebendazole or pyrantel pamoate
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13
Q

• Colorless, semi-transparent, with a finely striated cuticle, measuring 2.2mm x 0.04mm

A

Parasitic Female

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14
Q

Parasitic female

Anterior:
Posterior:

A

• Slender, tapering

• Short, conical, pointed tail

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15
Q

Parasitic Female

•_____ buccal cavity with___ indistinct lips

•______ esophagus extending to the anterior fourth of the body

•______ is continuous to the subterminal anus

•_____ at one-third the length of the body from posterior end

• Uteri contain single file of ____ ova

A

Short; 4

Long, slender

Intestine

Vulva

9-12 ova

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16
Q

Free-Living Female

• Reproduction:

A

Oviparous

17
Q

Parasitic Female

• Reproduction:

A

Parthenogenesis

18
Q

Free-Living Female

•_____ than parasitic female measuring 1mm x 0.06mm

• Muscular_____ esophagus

•_____ is straight cylindrical tube

A

Smaller

double-bulbed

Intestine

19
Q

Free-Living Male

• Smaller the female measuring 0.7mm x 0.04mm

•——- curved tail,_____ copulatory spicules, a______, no_____

• *Parasitic males are____

A

Ventrally; two; gubernaculum; caudal alae

not reliably identified

20
Q

Rhabditiform Larva

• Short buccal cavity, prominent genital primordium

A

Strongyloides stercoralis

21
Q

Rhabditiform

• Long buccal cavity, small genital primordium

A

Hookworm

22
Q

Filariform Larvae

• Short esophagus
• Pointed tail

A

• Hookworms

23
Q

Filariform larva

• Long esophagus
• Notched tail

A

Strongyloides stercoralis

24
Q

Ovum
Morphology

A

• Clear, thin, shell similar to hookworms

25
Q

Life cycle

Three Phases of Acute Infection

  1. Invasion of the___ by the_____
  2. Migration of larvae through the___
  3. Penetration of the ______by adult female worms
A

skin; filariform larvae

body

intestinal mucosa

26
Q

Skin

• Larva____

•_________ skin lesion at the side of entry caused by rapid moving filariform larva

• With_____&_____

A

currens

Erythematous serpiginous

pruritus and urticaria

27
Q

Migration of Larva

•_____

• Destroyed causing _______with hemorrhage

• Cough and tracheal irritation mimicking____

A

Lungs

lobar pneumonia

bronchitis

28
Q

: may be asymptomatic

A

• Light infection

29
Q

: diarrhea alternating with constipation

A

Moderate infection

30
Q

: intractable, painless, intermittent diarrhea characterized by episodes of watery and bloody stools (CochinChina Diarrhea)

A

Heavy infection

31
Q

: syndrome of accelerated autoinfection usually among immunocompromised

• Exacerbation of GIT and RT symptoms

• Increased number of larvae in stool samples and even in sputum

A

Hyperinfection

32
Q

Intestine

•_________

• Often asymptomatic

• May have intermittent vomiting, diarrhea, constipation, and borborygmi

• Anal pruritus, urticaria, larva currens

• Recurrent asthma, nephritic syndrome

A

Chronic strongyloidiasis

33
Q

Complications

A

• Edema, emaciation, anorexia, anemia, lobar pneumonia, ileus, intestinal obstruction, gastrointestinal bleeding, malabsorption

34
Q

Diagnosis

Clue: unexplained______

A

eosinophilia

35
Q

Diagnosis

Culture method

A

• Harada-Mori culture
• Nutrient agar plate

36
Q

Concentration techniques

Others:

A

Duodenal aspiration
Beale’s string test
small bowel biopsy

37
Q

Anti-helminths

• ______\contraindicated in pregnant women

•______: best for chronic uncomplicated strongyloidiasis

A

Albendazole, thiabendazole

Ivermectin

Parasitology Lec (31 decks)

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