Stomach Disorders

Question 1

Define dyspepsia

Answer 1

discomfort or pain in upper abdomen - indigestion

Question 2

Describe an EGD

Answer 2

esophagogastroduodenoscopy - upper endoscopy
- visual exam of upper digestive system with a tiny camera on a flexible tube
- requires sedation
- NPO prior to procedure
- risk of bleeding, infection, perf

Question 3

Describe the MOA of a PPI

Answer 3

suppress gastric basal & stimulated acid secretion

inhibit parietal cell H+/K+ ATP pump

Question 4

What are some concerns for long term PPI use

Answer 4

Question 5

List the MOA of H2 receptor antagonists

Answer 5

block histamine that stimulates the parietal cells of the stomach to produce acid, thus decreasing acid production

Question 6

What is the pathophysiology of barrett esophagus

Answer 6

squamous epithelium of esophagus replaced by metaplastic columnar epithelium (goblet cells and columnar cells)

Question 7

List some complications of GERD

Answer 7

• Barrett esophagus
• Peptic stricture

Question 8

Describe the etiology of gastritis

Answer 8

Question 9

Describe the etiology & presentation of erosive/hemorrhagic gastritis/gastropathy

Answer 9

Question 10

Describe the diagnosis & treatment of erosive/hemorrhagic stress gastritis

Answer 10

Question 11

Describe the alarm symptoms and treatment for NSAID gastritis

Answer 11

Question 12

Describe the etiology, presentation, & treatment for alcohol related gastritis

Answer 12

Question 13

Describe the etiology & diagnosis of non-erosive non-specific gastritis

Answer 13

Question 14

Describe the 3 types of h. pylori gastritis

Answer 14

Question 15

Describe the etiology & diagnosis of pernicious anemia gastritis (nonerosive)

Answer 15

Question 16

Describe the etiology of peptic ulcer disease

Answer 16

Question 17

Describe the presentation of peptic ulcer disease

Answer 17

Question 18

Describe the diagnosis of peptic ulcer disease

Answer 18

Question 19

Describe the treatment for peptic ulcer disease (& H pylori eradication)

Answer 19

Question 20

Describe the use of misoprostol in PUD

Answer 20

Question 21

Describe the standard bismuth quadruple therapy for H pylori eradication

Answer 21

Question 22

Describe the standard non-bismuth quadruple therapy for H pylori eradication

Answer 22

Question 23

Describe H pylori triple therapy

Answer 23

Question 24

List some non-pharm managements for PUD

Answer 24

• eat balanced meals at regular intervals (bland diet not needed
• moderate alcohol intake okay
• SMOKING CESSATION
• stop NSAIDs

Question 25

What is the most common reason for PUD recurrence

Answer 25

Failure to eradicate H pylori

Question 26

Describe functional dyspepsia

Answer 26

pain with no evidence of structural disease

Question 27

List some complications of PUD

Answer 27

hemorrhage, perforation, penetration, pyloric outlet obstruction

Question 28

Describe the etiology & presentation of zollinger-ellison syndrome

Answer 28

Question 29

Describe the diagnosis & treatment of zollinger ellison

Answer 29

Question 30

Describe the etiology of pyloric stenosis

Answer 30

Question 31

Describe the presentation of pyloric stenosis

Answer 31

Question 32

Describe the diagnosis & treatment of pyloric stenosis

Answer 32

Question 33

Describe the etiology of gastric adenocarcinoma

Answer 33

Question 34

Describe the presentation of gastric neoplasms

Answer 34

Question 35

Describe the diagnosis of gastric neoplasms

Answer 35