STG 2017 trial Flashcards
Management of torsades de pointes?
IV magnesium in haemodynamically stable, defib in haemodynamically unstable
What proportion of ALS patients have progressive cognitive abnormalities leading to dementia?
15-20%
How do SMART-COP scores correlate to intensive respiratory or vasopressor support (IRVS) requirements?
What percentage of gastrointestinal stromal tumours express activating mutations in c-KIT (CD117)?
>90%
What is the ideal gestation to start aspirin to reduce risk of early onset pre-eclampsia?
Between 12-14 weeks
How long does the Zika virus persist in semen for after symptoms resolve?
6 months
Does intention-to-treat analysis underestimate or overestimate the effect of the intervention?
Underestimates
What kind of immune reaction is post-strep GN?
Type III
What kind of lung cancer are cavitations associated with?
Squamous cell
What cell type is the most responsible for the interferon response to viral infections?
Plasmacytoid dendritic cells
What extra-intestinal manifestations parallel disease activity in IBD?
What does bite cells in haemolysis suggest?
Oxidative haemolysis
What is the BP cut off for ECR (stroke) ?
185/110
1st line for invasive aspergillosis
voriconazole
Next step in GIT bleeding without haemodynamic instability
Colonoscopy
What is the presentation of an anterior inferior cerebellar artery stroke?
ipsilateral horners + hearing loss
What is the active metabolite of azathioprine that is most associated with therapeutic efficacy?
6-TGN
Oral morphine: oral hydromorphone
5:1
What is the risk of developing superimposed pre-eclampsia on essential hypertension in pregnancy?
25%
What antibodies are thymoma myasthenia gravis associated with?
Titin and ryanodine receptor
What proportion of MG have a thymoma?
10%
What proportion of myasthenia gravis patients have pure ocular muscle involvement?
15%
What are the factors in the Glasgow-Blatchford score in risk stratification in UGIT bleeding?
- BUN
- Hb
- SBP
- HR
- Malaena
- Syncope
- Hepatic dysfunction
- Heart failure
What does HPC1 gene mutation cause?
Hereditary prostate cancer
What is the most commonly detected virus in the endomyocardial biopsies of patients with myocarditis?
Parovirus B19
What anti-hypertensive is most likely to contribute to erectile dysfunction in men?
Hydrochlorothiazide
How does calcium carbonate have to be taken with thyroxine?
4hr post thyroxine
Malaria prophylaxis
atovaquone+proguanil tablets (cont 7 days after leaving)
doxycycline (cont 14 days after leaving)
