STG 2017 trial Flashcards

1
Q

Management of torsades de pointes?

A

IV magnesium in haemodynamically stable, defib in haemodynamically unstable

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2
Q

What proportion of ALS patients have progressive cognitive abnormalities leading to dementia?

A

15-20%

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3
Q

How do SMART-COP scores correlate to intensive respiratory or vasopressor support (IRVS) requirements?

A
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4
Q

What percentage of gastrointestinal stromal tumours express activating mutations in c-KIT (CD117)?

A

>90%

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5
Q

What is the ideal gestation to start aspirin to reduce risk of early onset pre-eclampsia?

A

Between 12-14 weeks

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6
Q

How long does the Zika virus persist in semen for after symptoms resolve?

A

6 months

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7
Q

Does intention-to-treat analysis underestimate or overestimate the effect of the intervention?

A

Underestimates

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8
Q

What kind of immune reaction is post-strep GN?

A

Type III

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9
Q

What kind of lung cancer are cavitations associated with?

A

Squamous cell

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10
Q

What cell type is the most responsible for the interferon response to viral infections?

A

Plasmacytoid dendritic cells

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11
Q

What extra-intestinal manifestations parallel disease activity in IBD?

A
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12
Q

What does bite cells in haemolysis suggest?

A

Oxidative haemolysis

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13
Q

What is the BP cut off for ECR (stroke) ?

A

185/110

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14
Q

1st line for invasive aspergillosis

A

voriconazole

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15
Q

Next step in GIT bleeding without haemodynamic instability

A

Colonoscopy

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16
Q

What is the presentation of an anterior inferior cerebellar artery stroke?

A

ipsilateral horners + hearing loss

17
Q

What is the active metabolite of azathioprine that is most associated with therapeutic efficacy?

A

6-TGN

18
Q

Oral morphine: oral hydromorphone

A

5:1

19
Q

What is the risk of developing superimposed pre-eclampsia on essential hypertension in pregnancy?

A

25%

20
Q

What antibodies are thymoma myasthenia gravis associated with?

A

Titin and ryanodine receptor

21
Q

What proportion of MG have a thymoma?

A

10%

22
Q

What proportion of myasthenia gravis patients have pure ocular muscle involvement?

A

15%

23
Q

What are the factors in the Glasgow-Blatchford score in risk stratification in UGIT bleeding?

A
  1. BUN
  2. Hb
  3. SBP
  4. HR
  5. Malaena
  6. Syncope
  7. Hepatic dysfunction
  8. Heart failure
24
Q

What does HPC1 gene mutation cause?

A

Hereditary prostate cancer

25
Q

What is the most commonly detected virus in the endomyocardial biopsies of patients with myocarditis?

A

Parovirus B19

26
Q

What anti-hypertensive is most likely to contribute to erectile dysfunction in men?

A

Hydrochlorothiazide

27
Q

How does calcium carbonate have to be taken with thyroxine?

A

4hr post thyroxine

28
Q

Malaria prophylaxis

A

atovaquone+proguanil tablets (cont 7 days after leaving)

doxycycline (cont 14 days after leaving)