Stem Cells

Question 1

What is asymmetric division?

Answer 1

Stem cell division that reproduces one daughter committed cell and one stem cell

Question 2

How differentiated are precursor cells?

Answer 2

Partially

Question 3

Totipotent?

Answer 3

All cells of organism including embryo and extraembryonic

Question 4

Pluripotent?

Answer 4

All cells of embryo

Question 5

Multipotent?

Answer 5

Different cells of particular lineage

Question 6

What kind of potent are adult stem cells?

Answer 6

Multipotent

Question 7

Where do all blood cells come from?

Answer 7

From hematopoietic stem cells in marrow.

Question 8

How quickly do stem cells turn over in skin?

Answer 8

1-2 months

Question 9

What does Wnt signaling do to stem cell proliferation?

Answer 9

Increases it in a positive feedback loop. Long range signals inhibit outside of stem cell crypt

Question 10

What do stem cell niche cells do?

Answer 10

By staying attached to stem cell, signal it to remain stem cell. Adherens junctions

Question 11

3 key stem cell transcription factors?

Answer 11

Oct4, Sox2, Nanog