Sodium Bicarbonate 8.4%

Question 1

Pharmacology and presentation of Sodium Bicarbonate 8.4%?

Answer 1

100ml Glass Bottle

Sodium Bicarbonate is a hypertonic solution that acts as a buffer. Excess serum hydrogen ions react with the bicarbonate resulting in the formation of carbon dioxide and water. This action assists in restoring pH to within normal ranges.

Question 2

Indicators of Sodium Bicarbonate 8.4%?

• CCHT

Answer 2

• Tricyclic Antidepressant Overdose (TCA OD)
• Cardiac arrest secondary to TCA OD or hyperkalaemia
• Suspected hyperkalaemia, second line to Calcium Gluconate
• Crush Syndrome.

Question 3

Contraindications of Sodium Bicarbonate 8.4%?

Answer 3

• Known allergy.

Question 4

Cautions of Sodium Bicarbonate 8.4%?

-TIA

Answer 4

• Ensure adequate ventilation and perfusion to remove the excess CO2 produced
• Tissue necrosis if extravasation occurs
• Ensure IV lines as flushed, avoid mixing with other drugs or solutions.

Question 5

Side Effects of Sodium Bicarbonate 8.4%?

-RCC

Answer 5

• Cerebral oedema
• Congestive cardiac failure and pulmonary oedema.
• Can cause respiratory acidosis if adequate ventilation and circulation is not present.

Question 6

Dosing Regimes of Sodium Bicarbonate 8.4%?

Answer 6

Cardiac Arrest from TCA OD, Hyperkalaemia or Crush
- 100ml IV/IO, single dose

Question 7

Onset and duration of Sodium Bicarbonate 8.4%?

Answer 7

• Onset = Immediate
• Duration = Variable