Ipratropium Bromide

Question 1

Pharmacology and presentation of Ipratropium Bromide?

Answer 1

250microg/1ml Polyamp (Atrovent)

Anticholinergic bronchodilator, inhibits cholinergic broncho-motor tone, and blocks vagal reflex thus causing bronchodilation

Question 2

Indicators of Ipratropium Bromide?

Answer 2

• Moderate to severe asthma
• Exacerbation of COPD.

Question 3

Contraindications of Ipratropium Bromide?

Answer 3

• Known allergy
• Hypersensitivity to Atropine or its derivatives
• Age <1 year.

Question 4

Cautions of Ipratropium Bromide?

Answer 4

• Glaucoma
• Avoid contact with eye wherever possible.

Question 5

Side Effects of Ipratropium Bromide?

• STD HND

Answer 5

• Headache
• Nausea
• Dilated pupils
• Dry mouth
• Tachycardia and palpitations (rare)
• Skin rash.

Question 6

Dosing Regimes of Ipratropium Bromide?

Answer 6

Asthma, COPD & Bronchospasm
- Adults = single dose 500mcg Nebulised
- Paeds = single dose 250mcg Nebulised

Question 7

Onset and duration of Ipratropium Bromide?

Answer 7

• Onset = 1–3 minutes
• Duration = 4–6 hours