Calcium Gluconate 10%

Question 1

Pharmacology and presentation of Calcium Gluconate 10%?

Answer 1

953mg/10ml (2.2mmol) Ampoule

Calcium is an electrolyte that is involved in skeletal muscle contraction, excitation coupling in cardiac and smooth muscle and acts as an intracellular second messenger. These effects combine to exert a positive inotropic effect in the post-cardiac arrest patient. It additionally has a role in cardiac membrane stabilisation in hyperkalaemia. It is used in the treatment of hypermagnesaemia.

Question 2

Indicators of Calcium Gluconate 10%?

2x Potassium
1x Mag
1x Calcium
1x Blood

Answer 2

• Suspected hyperkalaemic cardiac arrest
• Severe hyperkalaemia with significant cardiac rhythm disturbance
• Hypotension or toxicity associated with magnesium infusion
• Calcium channel blocker toxicity
• Following pre-hospital blood administration.

Question 3

Contraindications of Calcium Gluconate 10%?

-AD

Answer 3

• Known allergy
• Digoxin (Digitalis) overdose.

Question 4

Cautions of Calcium Gluconate 10%?

Answer 4

• Respiratory Acidosis

Question 5

Side Effects of Calcium Gluconate 10%?
- 4x Heart 1x Head

Answer 5

• Syncope
• Hypotension
• Bradycardia
• Cardiac Dysrhythmia
• Cardiac arrest.

Question 6

Dosing Regimes of Calcium Gluconate 10%?

Answer 6

Suspected hyperkalemic CA
- Adult = 10ml IV/IO once

Question 7

Onset and duration of Calcium Gluconate 10%?

Answer 7

• Onset = 1–3 minutes
• Duration = 30–60 minutes