Loratadine

Question 1

Pharmacology and presentation of Loratadine?

Answer 1

10mg Tablet

H-1 receptor antagonist (Non-sedating anti-histamine), blocks peripheral histamine receptors, and reducing itchiness/redness

Question 2

Indicators of Loratadine?

Answer 2

• Mild allergic reaction (rash) without evidence of anaphylaxis.

Question 3

Contraindications of Loratadine?

Answer 3

• Known allergy
• Anaphylaxis.

Question 4

Cautions of Loratadine?

Answer 4

• Severe liver impairment
• Increased risk of sedation and anticholinergic effects in older people.

Question 5

Side Effects of Loratadine?

• 3x sleepy 2x mouth

Answer 5

• Drowsiness
• Fatigue
• Headache
• Nausea
• Dry mouth.

Question 6

Dosing Regimes of Loratadine?

Answer 6

• > 8years = 10mg PO, single dose avoiding further administration within 24hrs

Question 7

Onset and duration of Loratatdine?

Answer 7

• Onset = 15 minutes
• Duration = 4–6 hours