Ibuprofen

Question 1

Pharmacology and presentation of Ibuprofen?

Answer 1

200mg Tablet
100mg/5ml liquid

Ibuprofen is a NSAID, predominantly used as an analgesic. Inhibits prostaglandin synthetase, reducing prostaglandin production and causing a reduction in inflammation, pain and fever.

Question 2

Indicators of Ibuprofen?

Answer 2

• Mild to moderate pain secondary to inflammation or soft tissue injury.

Question 3

Contraindications of Ibuprofen?

• A HARDPACK

Answer 3

• Known allergy
• Current gastrointestinal bleeding or peptic ulcer
• Dehydration and/or hypovolaemia
• Renal impairment
• Heart failure
• Pregnancy
• Pt taking anticoagulants
• Age <13 or >65 years
• Patients on ACE Inhibitors or Angiotensin II Receptor blocker drugs.

Question 4

Cautions of Ibuprofen?
- LAG

Answer 4

• Asthma
• Liver dysfunction
• History of gastrointestinal bleeding or peptic ulcers.

Question 5

Side Effects of Ibuprofen?
- 2x head 2x stomach

Answer 5

• Nausea
• Dyspepsia
• Gastrointestinal bleeding
• Dizziness.

Question 6

Dosing Regimes of Ibuprofen?

Answer 6

Analgesia
- 200-400mg PO, single dose only, do not administer if previously had it within last 6 hrs

Question 7

Onset and duration of Ibuprofen?

Answer 7

• Onset = 15 minutes
• Duration = 4–6 hours