senses and perception Flashcards
what is the required input for tactile input?
- quality (type of touch)
- magnitude, intensity
- duration, timing
- location
how does a stimulus reach the brain?
action potential through modality-specific sensory receptors
describe the structure of a sensory nerve cell
- cell body
- axon with a receptor ending (periphery) and central terminal (CNS)
what are the three categories within sensory mechanisms?
- types of receptors
- transduction of stimulus
- coding of stimulus properties
what type of receptor does a mechanical stimulus act on and what is the sensation?
mechanoreceptor, touch
what type of receptor does a thermal stimulus act on and what is the sensation?
thermoreceptor, temperature
what type of receptor does a noxious stimulus act on and what is the sensation?
nociceptor, pain
what type of receptor does a chemical stimulus act on and what is the sensation?
chemoreceptor, taste/smell
what type of receptor does a light stimulus act on and what is the sensation?
photoreceptor, sight/vision
describe free nerve endings
- unspecialised
- characteristic nociceptors
- pain stimuli
what are the different types of receptor endings in the skin?
- free nerve ending
- mechanoreceptors:
meissners corpuscle
merkel disk
hair follicle receptor- deflection of hair
pacinian corpuscle- vibration, slip
ruffini endings- vibration, slip
what defines a neuron’s receptive field?
distribution of the receptor endings
what ensures complete coverage of our external areas with sensory neurons?
overlapping receptive fields
are all receptive fields similar in size?
no, varies in regions eg small on fingertips and periphery, large on limbs and proximal surfaces
what is two point discrimination?
the ability to discern two separate mechanical stimuli from eachother
what does two point discrimination allow?
- a measure of spatial resolution
- an indication of receptive field size
when stimuli are in two different receptor fields, what is felt?
sensation at two different points
what happens when there are two stimuli in one receptor field?
the sensation is only felt at one point
what is the temporal sequence of stimulus tranduction?
- stimulus to skin
- activation or appropriate receptor ending
- change in receptor membrane permeability
- influx of cations
- membrane depolarisation (receptor potential)
- if sufficient, causes an action potential
- action potential relayed to CNS
what is the normal value for resting potential?
-70mV
what are the receptor subtypes?
- ionotropic
- G-coupled
what are the properties of ionotrphic receptors?
- fast kinetics
what are the properties of G-protein coupled receptors?
- slow kinetics
what are the modalities of ionotrophic receptors?
mechanoreceptors and chemoreceptors
what are the modalities of G-protein coupled receptors?
chemoreceptors
how is a stimuli transduced in ionotrophic mechanoreceptors?
- ion pore in cell membrane
- closed when inactive
- becomes active on a mechanical stimulus due to deformation of cell membrane
- pore opens and sodium and potassium can flow
- leads to an action potential
how is a stimuli transduced in ionotrophic chemoreceptors?
- ion pore in cell membrane
- too narrow when inactive
- ligand binding receptor sites on extracellular side
- when bound to, pore is activated and opens wider
- sodium and potassium ions can flow
- can generate an action potential
how is a stimuli transduced in G-protein coupled chemoreceptors?
- pore through cell membrane
- ligand binding site on extracellular membrane
- binding causes activation of the pore via intracellular proteins
- sodium and potassium can flow
- can generate an action potential
why is a G-protein coupled receptor stimulus slower?
more complex to open pore for action potential