alimentary control Flashcards

1
Q

what are the nerve divisions involved in alimentary control?

A

somatic (voluntary)
- sensory
- motor
autonomic (involuntary)
- sympathetic
- parasympathetic

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2
Q

what are the hormones in the GIT?

A
  • cholecystokinin (CCK)
  • gastrin
  • gastric inhibitory peptide (GIP)
  • secretin
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3
Q

where is CCK secreted from and what is its function?

A

the duodenum endocrine cells
- functions to help digest fats and proteins

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4
Q

where is gastrin secreted from and what is its function?

A

G cells in the stomach
- functions to stimulate HCL by parietal cells

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5
Q

what is the function of GIP?

A

increases insulin secretion

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6
Q

what is the function of secretin?

A

increase HC03 (bicarbonate) from the pancreas

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7
Q

where are hormones most active?

A

at the level of the stomach

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8
Q

what is secretory control done by?

A

entirely neural via some cranial nerves

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9
Q

what are the cranial nerves involved with chemical taste and smell secretion control?

A

taste- 7 and 9
smell- 1

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10
Q

what cranial nerve is involved with mechanical chewing secretion control?

A

loading periodontal ligaments CN 5

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11
Q

what are the stimuli involved with salivatory secretion?

A
  • vision
  • olfactory (smell)
  • mechanical (chewing)
  • chemical (taste)
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12
Q

what muscles are involved in chewing?

A

jaw, facial and tongue muscles

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13
Q

which cranial nerves are involved in chewing?

A

5, 7, 12

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14
Q

what muscles are involved in swallowing?

A

jaw, tongue and pharyngeal muscles

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15
Q

what cranial nerves are involved with swallowing?

A

5, 9, 10 and 12

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16
Q

what muscles are involved in the oesophagus?

A

mix of skeletal and smooth muscle

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17
Q

what cranial nerve is involved with the oesophagus?

A

10- vagus

18
Q

what are the functions of the stomach?

A
  • secretion (gastric juice)
  • motility (filling, relaxation, mixing, peristalsis, emptying)
19
Q

what are the stimuli of gastric activity?

A

cephalic phase
- mechanical chewing (muscles of mastication)
- chemical (taste, smell)
- psychic (visual, emotional)
gastric phase- stimulates secretion
- mechanical (distension)
- chemical (food in stomach)
intestinal phase
- mechanical (distension)
- chemical (acid, protein in duodenum)

20
Q

what is distension?

A

knowing you’re full

21
Q

what are the controls of gastric activity?

A

cephalic phase
- nerves (long reflex)
gastric phase
- nerves (long & short reflexes)
- hormones (gastrin)
intestinal phase
- nerves (long & short reflexes)
- hormones (GIP and secretin)
- tends to slow gastric emptying

22
Q

short vs long nerve reflexes

A

long- to brain
short- locally at that site

23
Q

what are the functions of the small intestine?

A
  • absorption
  • secretions (intestinal juice)
  • motility (mixing, villus movements, segmentation contractions, peristalsis)
24
Q

what are the controls of the small intestine?

A

mainly by local nerves/short reflexes in response to intra-luminal stimuli

25
Q

describe the role of bicarbonate in pancreatic juice

A

Intestinal phase
- secretin (released from the duodenum in response to acid to neutralise, stimulates secretion of bicarbonate rich pancreatic juice)
- CCK and VIP- weaker stimulation of bicarbonate

26
Q

what is CCK?

A

Cholecystokinin (bile sac mover) and mainly works by promoting the digestion of fat and protein. It also is an appetite suppressant.- stimulates secretion of bicarbonate, enzyme rich pancreatic juice

27
Q

what is VIP?

A

Vasoactive intestinal polypeptide – many functions and production sites but for the gut it breaks down glycogen and relaxes the smooth muscle of the gall bladder and the stomach.

28
Q

where is gastrin released from?

A

g cells in the stomach, duodenum and pancreas

29
Q

what is the function of gastrin?

A

increases the secretion of HCl by the parietal cells in the stomach

30
Q

what is GIP?

A

Gastric Inhibitory Peptide (Polypeptide) – weak inhibition of stomach acid secretion, but actually stimulates insulin secretion, stops death of pancreatic beta cells (insulin producing cells), stimulates glucagon and also accumulation of fat.

31
Q

what are patients with their gallbladder removed advised?

A

to reduce their fat intake

32
Q

secretion of bile CCK

A
  • Stimulates contraction of gall bladder (gall bladder needed to store bile)
  • relaxation of the sphincter of oddi
33
Q

what are the functions of the large intestine and rectum?

A
  • secretions (mucus to protect, water and electrolytes)
  • motility (mixing, mass movements- peristalsis and defaecation)
34
Q

describe neural control in the large intestine

A
  • mixing and segmentation is controlled by local reflexes
  • long reflexes are triggered by food entering the stomach- increases motility in the intestine
  • gastro-ileal reflex- gastric activity increases motility in the ileum
  • gastro-colic reflex- gastric activity increases motility on the colon
34
Q

describe neural control in the large bowel

A
  • mixing and segmentation is controlled by local reflexes
  • long reflexes are triggered by food entering the stomach- increases motility in the intestine
  • gastro-ileal reflex- gastric activity increases motility in the ileum
  • gastro-colic reflex- gastric activity increases motility on the colon
35
Q

describe control in the large intestine and rectum

A
  • mainly nueral
  • ANS, Vagus, pelvic nerves
36
Q

describe control in the rectum

A
  • ANS control of internal and sphincter
  • voluntary control of external sphincter
  • somatic nerves
37
Q

what are the two main anal sphincters?

A

internal and external

38
Q

what is the internal anal sphincter controlled by

A

parasympathetic fibres which relax involuntarily

39
Q

what type of muscle is the external anal sphincter?

A

skeletal muscle

40
Q

what controls the external anal sphincter?

A

somatic nerves from the inferior anal branch of the pudendal nerve- allows conscious control of defecation

41
Q

what are the reflexes which take place is defecation is appropriate?

A

Relaxation of the external sphincter
Contraction of abdominal wall muscles
Relaxation of pelvic wall muscles
Peristaltic waves then facilitate the movement of faeces through the anal canal.