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Immunology and Microbiology > Rhinovirus > Flashcards

Rhinovirus Flashcards

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Biology 101 flashcards
1
Q

the rhinovirus causes

A

the common cold

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2
Q

there are more than ______ viruses that cause the common cold

A

200

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3
Q

young children average how many colds per year?

adults?

A

6-8

2-4

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4
Q

how many cases of the common cold are in the US per year?

A

62 million cases

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5
Q

how many stereotypes are there for rhinovirus?

and what does this mean?

A

over 115 distance stereotypes

repeated infections! hard to come up with a vaccine

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6
Q

rhinovirus is part of the

A

picornavirus family

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7
Q

rhinovirus

A

ss plus strand RNA
non-enveloped

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8
Q

rhinovirus replication

A

APUMAR

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9
Q

ICAM-1

A

intercellular adhesion molecule-1
expressed on epithelial cells, endothelial cells and fibroblasts
binds to canyon

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10
Q

ICAM-1 binding initiates

A

uncoating

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11
Q

experimental drug to inhibit binding

A

prevent ICAM-1 from binding in the pocket in capsid
involves VP4
competitive inhibition

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12
Q

Rhinovirus transmission

A

aerosols and fomites

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13
Q

infectious dose of rhinovirus

A

as low as 1 virus particle

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14
Q

major mode of transmission of rhinovirus

A

person to person via hands

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15
Q

how long can rhinovirus survive outside of the human body

A

48 hours

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16
Q

symptoms of rhinovirus compared to influenza and covid-19

A

common cold - sore throat and sneezing; NO chills or fever
influenza - NO sore throat or sneezing
Covid-19: NO sneezing

17
Q

who is at higher risk for rhinovirus

A

infants and young children
immunocompromised

18
Q

season for rhinovirus

A

early autumn through late spring

19
Q

treating the common cold

A

rest
fluids
clean humidifier
avoid smoking/pollutants
take non-aspirin pain reliever
saline nasal spray/drops

20
Q

can sleep protect against the common cold?

A

YES!

so get some sleep ladies!

21
Q

common cold includes

A

rhinoviruses
parainfluenza virus
respiratory syncytial virus (RSV)
COVID

Immunology and Microbiology (18 decks)

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