Reproductive [Female] Flashcards

1
Q

Vagina 3 main functions

A

Elimination of menstrual fluids.
Receives penis.
Holds sperm before they go to uterus.

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2
Q

Uterus functions

A

Pathway for sperm transport.
Protection, nutrition, waste removal for fetus.
Contractions in myometrium for birth.

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3
Q

Uterus endometrium - 2 layers and what they contain

A

Stratum functionalis that contains most uterine glands.

Stratum basalis: attaches to myometrium.

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4
Q

Where does fertilisation occur?

A

Ampulla of the uterine tube.

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5
Q

Uterine tube function

A

Rich, nutritive environment with lipids and glycogen for sperm, oocyte and embryo.

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6
Q

What is the uterine tube lined with?

A

Ciliated and nonciliated secretory columnar cells. Mucous surrounded by smooth muscle.

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7
Q

Ovaries 3 regions and what contains

A

Outer ovarian cortex: ovarian follicles.
Central ovarian medulla: ovarian stroma and steroid producing cells.
Inner hilus: entry of nerves and vessels.

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8
Q

What is the top of the oval that is a part of the uterus?

A

Fundus

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9
Q

Primordial follicle:

A

Primordial follicle: single layer of flat follicular cells

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10
Q

Primary follicle:

A

Primary follicle: one layer of granulosa. Vessels, theca, zona pellucida

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11
Q

Secondary follicle: What does it have? The ______ develops to become the _______ ______and the surrounding _____ , the _____.

A

Secondary follicle: corona radiata, antrum and cumulus oophorus. The theca develops to become the inner glandular, highly vascular theca interna and the surrounding fiborous capsule, the theca externa.

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12
Q

Mature (Graafian) follicle: As the follicular antrum grows, the oocyte becomes _____. It is connected to the rim of ________ by a _____.

A

Mature (Graafian) follicle: As the follicular antrum grows, the oocyte becomes suspended in fluid. It is connected to the rim of peripheral granulosa cells by a thin stalk of cells.

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13
Q

What is the name for the ruptured follicle before the secondary oocyte is discharged?

A

Corpus hemorrhagicum.

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14
Q

How is the corpus luteum formed? What is secreted at the same time?

A

Antrum breaks down, BM between gran. and thecal cells breaks down and blood vessels invade. Gran. cells form lutenin (yellow cells) = lutenisation. Progestagens secreted.

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15
Q

What is the corpus albicans? What happen to it?

A

The white scar tissue remaining after lutenisation. It’s absorbed back into the stromal tissue of the ovary over weeks-months.

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16
Q

What happens to the corpus luteum if the oocyte is fertilized?

A

It gets to live for longer than 2 weeks! Chorion of Embryo secretes hCG to save it.

17
Q

What are thecal cells? When do they appear?

A

Thin layer of condensed ovarian stromal cells. Appear in the primary (pre-antral) follicle.

18
Q

What are the two stages of the ovarian cycle? When?

A
Follicular phase (day 1 to ovulation).
Luteal phase (ovulation to menstruation.)
19
Q

3 stages of endometrial cycle

A

Menstrual, proliferative, secretory.

20
Q

About day 6-7, there is ______, with increased _____.

A

About day 6-7, there is selection of the dominant follicle with increase oestrogen.

21
Q

Oestrogen levels rise and reach a threshold which is exceeded at day ____. If this is maintained, there is a _______.

A

Oestrogen levels rise and reach a threshold which is exceeded at day 12. If this is maintained, there is a temporary switch from negative to positive feedback.

22
Q

What are the 3 steps to ovulation after high levels of Oestrogen are reached?

A
  1. High levels stimulate release of more GnRH and LH.
  2. GnRH remotes release of FSH and more LH.
  3. LH surge brings about ovulation.
23
Q

What inhibits GnRH and what does this lead to?

A

Elevated progesterone levels due to development of corpus luteum. Leads to decreased FSH and LH.

24
Q

Ectopic pregnancy 3 risk factors

A

Smoking
Ageing
Prior tubular damage

25
Q

The very outside of the ovarian cortex is called the ____

A

Germinal epithelium

25
Q

The layer just inside the germinal epithelium of the ovarian cortex is called _____

A

Tunica albuginea

26
Q

What secretes glycoproteins?

A

Oocyte to make zona pellucida