Renal System Meds

Question 1

Function of a Urinary Tract Antiseptic

Answer 1

Inhibit growth of bacteria in the urine. Used to treat UTIs and acute cystitis.

Question 2

Nitrofurantoin

Answer 2

Urinary tract antiseptic, should be taken with food, turns the urine brown. Contraindicated in patients with renal impairment.

Question 3

Function of Floroquinolones

Answer 3

Suppress bacterial growth by inhibiting an enzyme which enables DNA synthesis. Types include ciprofloxacin, levofloxacin, ofloxicin and norfloxacin. Administer with a full glass of water and increase fluid intake to minimize development of crystaluria.

Question 4

Side effects of Floroquinolones (Ciprofloxacin)

Answer 4

Dizziness, visual disturbance and light sensitivity indicate CNS toxicity

Question 5

Sulfonomides

Answer 5

Suppress bacterial growth by inhibiting folic acid synthesis. Types include sulfadiazine, trimethoprim, sulfamethoxazole. Take on an empty stomach with a full glass of water. Withhold if rash appears.

Question 6

Side effects of trimethoprim and sulfadiazine

Answer 6

Rash, fever, photosensitivity, leukopenia, thrombocytopenia

Question 7

Function and side effect of hemopoietic growth factors

Answer 7

Stimulate the production of red blood cells. Used to treat anemia in CKD. Major side effect is hypertension.