Cardiovascular Meds Flashcards
Function of Anticoagulants
Prevent clot formation and thromboembolism.
Normal aPTT
20-36 seconds
Heparin sodium
Anticoagulant. Therapeutic at 1.5 to 2.5 the normal aPTT time
Warfarin sodium
Anticoagulant. Suppresses coagulation by acting as a vitamin k agonist and suppressing 4 clotting factors.
PT is 1.5-2 times the normal value.
INR is 2-3 or 4-5 for patients on warfarin.
Normal INR
1.3-2.0
Normal PT
9.5-11.5 seconds
Function of Thrombolytic medications & used to treat what
Used to dissolve clots. Can be used to treat MI within 4-6 hours of occurrence. Also used to treat PE and DVT.
Function of Anti-platelet medications
Inhibit the aggregation of platelets thereby increasing clotting time.
Types of anti-platelet medications
Aspirin & clopidogrel
Types of positive inotropic and cardiotonic meds
Dopamine, dobuatmine
Function of positive inotropic and cardiotonic meds
Stimulate myocardial contractility
Cardiac Glycosides
Inhibit the Na/K pump and causing the heart to contract more efficiently, increased the force of contracting and reduces the heart rate.
Type of cardiac glycosides
Digoxin
Digoxin therapeutic range
0.5-2.0. If >2.0 then toxicity.
Anti-hypertensive medications
Diuretics. Affect Na+ and H20 reabsorption in the kidneys.
ACE Inhibitor functions
Prevent peripheral vasoconstriction thereby reducing blood pressure.
Types of ACE Inhibitors
Ramipril
Beta blocker functions
Block the release of catecholamines - epinephrine and norephiepherine to reduce heart rate and blood pressure.
Types of beta blockers
Propranolol, bisoprolol, atenolol.
Calcium channel blockers function
Promote vasodilation of coronary and peripheral vessels.