Cardiovascular Meds Flashcards
Function of Anticoagulants
Prevent clot formation and thromboembolism.
Normal aPTT
20-36 seconds
Heparin sodium
Anticoagulant. Therapeutic at 1.5 to 2.5 the normal aPTT time
Warfarin sodium
Anticoagulant. Suppresses coagulation by acting as a vitamin k agonist and suppressing 4 clotting factors.
PT is 1.5-2 times the normal value.
INR is 2-3 or 4-5 for patients on warfarin.
Normal INR
1.3-2.0
Normal PT
9.5-11.5 seconds
Function of Thrombolytic medications & used to treat what
Used to dissolve clots. Can be used to treat MI within 4-6 hours of occurrence. Also used to treat PE and DVT.
Function of Anti-platelet medications
Inhibit the aggregation of platelets thereby increasing clotting time.
Types of anti-platelet medications
Aspirin & clopidogrel
Types of positive inotropic and cardiotonic meds
Dopamine, dobuatmine
Function of positive inotropic and cardiotonic meds
Stimulate myocardial contractility
Cardiac Glycosides
Inhibit the Na/K pump and causing the heart to contract more efficiently, increased the force of contracting and reduces the heart rate.
Type of cardiac glycosides
Digoxin
Digoxin therapeutic range
0.5-2.0. If >2.0 then toxicity.
Anti-hypertensive medications
Diuretics. Affect Na+ and H20 reabsorption in the kidneys.
ACE Inhibitor functions
Prevent peripheral vasoconstriction thereby reducing blood pressure.
Types of ACE Inhibitors
Ramipril
Beta blocker functions
Block the release of catecholamines - epinephrine and norephiepherine to reduce heart rate and blood pressure.
Types of beta blockers
Propranolol, bisoprolol, atenolol.
Calcium channel blockers function
Promote vasodilation of coronary and peripheral vessels.
Types of calcium channel blockers
Amlodopine, verapamil
Peripheral vasodilator - function
Reduce peripheral resistance by dilating arteries and veins increasing blood flow to extremities.
Antilipemic medications
Reduce cholesterol, triglycerides and LDL
Types of antilipemic medications
Atorvastatin, simvastatin
Heparin sodium - type of med
anticoagulant
Warfarin - type of med
anticoagulant
Aspirin - type of med
anti platelet
Clopidogrel - type of med
anti platelet
Dopamine - type of med
Positive inotropic
Diuretics - type of med
anti-hypertensive
Ramipril - type of med
ACE inhibitor
Propranolol - type of med
Beta blocker
Bisoprolol - type of med
Beta blocker
Amlodipine - type of med
Calcium channel blocker
Atorvistatin - type of med
cholesterol
Simvastatin
cholesterol
Symptoms of digoxin toxicity
- GI (n&v, diarrhea,)
- Anorexia
- headache
- visual disturbances
Irbesartan
Treats hypertension
Prazocin
Anti-hypertensive
Moexipril & Captopril - when to take
1 hour before meals
What bloods should you monitor on a patient taking statins?
CBC
Verapamil - what type of drug
Calcium channel blocker
Side effect of verapamil
constipation
Major side effect of spironolactone
Hyperkalemia (potassium sparing diuretic)
Prior to administering beta blockers check the patient’s….
apical heart rate
Beta blockers can induce
bronchospasm
Thiazide side effects
- Hypokalemia
- Hyperglycemia
- Hypercalcemia
- Hyperuricemia
Heparin antidote
Protamine sulfate
Warfarin antidote
Vitamin K
Thrombolytic antidote
Aminocaproic acid
Side effects of Beta blockers
- dizziness
- nausea
- diaphoresis
- headache
- cold extremities
- fatigue
- constipation or diarrhea.
Occasional side effects include insomnia, flatulence, urinary frequency, and impotence or decreased libido
If a patient is on thyroid medication, how does this affect their warfarin prescription?
The amount of warfarin prescribed should be reduced.