Maternity and Newborn Medications Flashcards
Tocolytics
Medication that relaxes the uterus and surpasses uterine activity to help prevent pre-term labor.
Adverse effects of tocolytics
- N &V
- Hypotension
- Dizziness
- Tachycardia
- Headache
Types of tocolytic drugs
- Intocin
- Magnesium Sulfate
- Pericardia
- Adalat
- Nifedical
- Terabutaline
Maternal contraindications for tocolytic drugs
- Eclampsia and preeclampsia
- Active vaginal bleeding
- Intrauterine infection
- Cardiac Disease
Fetal Contraindications for tocolytic drugs
- 37+ weeks gestation
- Cervix 4+cm dilated
- Uterine growth restriction
- Fetal distress
Magnesium Sulfate
Central Nervous System depressant and anticonvulsant. Causes smooth muscle to relax. Used to stop preterm labor and prevent seizures in eclampsia. Antidote is calcium gluconate.
Adverse effects of magnesium sulfate
- Respiratory distress
- Hypotension
- Muscle weakness
- Pulmonary edema
Magnesium sulfate administration
Through an infusion pump.
Keep calcium gluconate on hand.
Check patellar reflex prior to administration.
Respirations > or = 16bpm
Betamethasone & Dexamethasone
Corticosteroids that increase the production of surfactant to accelerate fetal lung maturity and decrease respiratory distress.
When can corticosteroids be used?
In patient in preterm labor between 28-32 weeks whose labor can be inhibited for 48 hours with no detriment to mother or fetus.
Contraindications for corticosteriods
- Lowers maternal resistance to infection.
- Pulmonary edema (Na and H20 retention)
- Increase in blood glucose in diabetic patients.
How are corticosteroids administered?
IM injection
How are opioid analgesics administered?
IM injection
What is the antidote for opioid toxicity?
Naloxone rapidly reverses opioid toxicity.
Types of opioid analgesics
- Demerol
- Dilaudid
- Fentanyl
- Sufenta
- Butorphanol tartrate
- Nalbuphine
Contraindications for opioid analgesics
- N & V
- Dizziness
- Hypotension
- respiratory depression
- cyanosis
- coma
- fetal narcosis
- fetal distress
When is Butorphanol tartrate contraindicated and why?
In patients with previous history of opioid dependency it can cause withdrawal symptoms.
Prostaglandins
Medication that makes the cervix softer by dilation and effacement.
How are prostaglandins administered?
Vaginally.
Types of prostaglandins
- Cyotec
- Cerdivil
- Prostin
Contraindications of prostaglandins
- N & V
- Diarrhea
- Cramps
- Fever & chills
- Flushing
- Fetal passage of mycelium
- Hyperstimulation of the uterus
- Tachystystole
Uterine Stimulants
Include oxytocin (pitocin) which stimulate the smooth muscle of the uterus to increase force, frequency and duration of contractions.
Medications for postpartum hemorrhage
- Ergot alkaloids
- Prostaglandin F
- Oxytocin
Ergot alkaloids
Stimulate uterine contractions and produce arterial vasoconstriction.
Includes:
- ergonovine maleate
- methylergonovine maleate
When should you stop pitocin infusion?
When there is hyperstimulation of the uterus.
Contraindications for postpartum hemorrhage medications
- During pregnancy
- Cardiovascular disease
- PVD
- Hypertension
Side effects of postpartum hemorrhage medications
- Nausea
- Cramping
- bradycardia
- Dysrhythmias
- MI
- Hypertension