Renal Flashcards by Mary Nolastname

Q

spikes in GBM

A

membranous glomerulonepropathy

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Q

JG cells

A

smooth muscle cells with renin granules

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Q

renal hypoperfusion

A

increase renin secretion by JG cells

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Q

low C3

A

PSGN

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Q

eosinophilic casts

A

Bence Jones + Tam Horsfall protein (multiple myeolma)

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Q

finasteride

A

5 alpha reductase inhibitor

decrease prostate volume

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Q

alpha3 chain of type IV collagen

A

good pastures

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Q

lumpy bumpy apperance

A

PSGN

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Q

salicylate toxicity

A

resp alkalosis followed by metabolic acidosis

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Q

rubber manufacturing

A

transitional cell bladder cancer

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Q

polycystic renal disease

A

decrease vit D

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Q

Inulin

A

freely filtered

not reabsorbed or secreted

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Q

FF =

A

GFR/RPF or

GFR / (1 - hct) x RBF

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Q

PAH

A

excreted amount&raquo_space; filtered

net secretion

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Q

PAH lowest concentration

A

bowman’s capsule

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Q

loss of antithrombin III

A

thromboembolic events

flank pain, gross heamturia

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Q

filtration rate =

A

inulin clearance x plasma concentration

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Q

excretion rate =

A

inulin clearance x plasma concentration - tubular reabsorption

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Q

RPGN cells

A

monocytes, macrophages, FIBRIN

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Q

interstitial nephritis

A

penicillins, NSAIDs

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Q

RCC paraneoplastic syndromes

A

EPO
ACTH
PTH

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Q

transitional cell carcinoma associatins

A

phenacetin
smoking
aniline dyes
cyclophophamide

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Q

RPGN

A

1 - GP
2 - immune complex
3 - wegners

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Q

IgA deposits

A

Berger’s dz

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Q

DPGN

A

SLE

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Q

MPGN

A

HBV, HCV

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Q

FSGS

A

HIV

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Q

membranous nepropathy

A

SLE
infections
solid tuors

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Q

RBC casts

A

glomerulonephritis

Q

WBC casts

A

trnasplant rejection

pyelonephritis

Q

fatty casts

A

nephrotic syndrome

Q

granular casts/muddy brown casts

A

ATN

Q

afferent arteriole constriction

A

decrease RPF, GFR

Q

efferent arteriole constriction

A

decrease RPF

increase GFR

Q

horseshoe kidney

A

turner’s association

Q

potter’s syndrome association

A

posterior urethral valves

ARPKD

Q

Clearance < GFR

A

reabsorption

Q

Clearance > GFR

A

secretion

Q

Renal Plasma Flow Calculation

A

RPF = urine PAH x urine flow rate / plasma PAH

Q

Renal Blood Flow Calculation

A

Renal Plasma Flow / 1 - HCT

Q

increase plasma protein concentration

A

decrease GFR

Q

decrease plasma protein concentration

A

increase GFR

Q

Aldosterone

A

reabsorps Na

secrete K and H

Q

Foscarnet

A

CMV retinitis treatment

causes hypocalemia and hypomagnesium

Q

PLA2R Antibodies

A

gluomerulonephritis = membranous nephropathy

Q

RCC originates from

A

proximal renal tubules

Q

early detection of diabetic neuropathy

A

microalbuminemia

Q

mannitol

A

used for cerebral edema

side effect - pulmonary edema

Q

vasopression/ADH acts on

A

medullary segment of collecting ducts

Q

CKD manifestations

A

low calcium –> osteodystrophy

Q

Amph B side effects

A

hypokalemia and hypomagnesium

Q

ATN initiation

A

ischemic injury

Q

ATN maintenance

A

decreased urine
increase CR/BUN
hyperkalemic

Q

ATN recovery

A

low K, Mg, Po4, Ca

Q

MCD - type of proteinuria

A

selective

albumin loss&raquo_space;> bulky proteins

Q

tubular re-epithelization is outcome of

A

ATN

Q

impermeable to H20

A

ascending limb

Q

PSGN prognosis

A

better with younger age

Q

Neprhotic Syndrome

A

proteinuria
hypoalbuminemia
hyperlipidemia

Q

Nephrotic Syndrome caused by

A

decreased oncotic pressure

Q

clear cell has

A

high lipid/glycogen content

Q

substances that are neither secreted or reabsorbed

A

mannitol

inulin

Q

substances that are reabsorbed

A

glucose
urea
sodium

Q

substances that are secreted

A

PAH

creatinine

Q

ceramid trihexoside accumulation

A

Fabry Disease

Q

Fabry disease

A

angiokeratomas

renal failure

Q

primase

A

RNA polymerase

Q

lactic acidosis decreases what enzyme

A

pyruvate DH

Q

aceI cause

A

constriction of efferent arteriole
vasoconstriction
aldosterone

Q

uric acid precipitation

A

due to low urine PH

DCT, CD

Q

metameniphic mesoderm becomes

A

glomeruli
bowman’s capsule
PCT, loop of henle, DCT

Q

ureteric bud becomes

A

CTubules, CDuct

calyces, renal pelvis, ureters