Immune System Missed Concepts

Question 1

cells with MHC1

Answer 1

all except RBCs

Question 2

CD3

Answer 2

T cell

Question 3

CD28

Answer 3

T cell

binds B7 on APC

Question 4

CD4, 40

Answer 4

helper t cells

Question 5

CD8

Answer 5

cytotoxic t cells

Question 6

B cells

Answer 6

CD 19,20,21, 40

Question 7

CD16

Answer 7

NK cells

Question 8

CD56

Answer 8

NK cells

Question 9

Anaphyaxis

Answer 9

C3a, C5a

Question 10

Classic Complement pathways

Answer 10

IgG or IgM

Question 11

APCs

Answer 11

dendritic cells
macrophages
B cells

Question 12

Kaposi sarcoma associated with

Answer 12

black colored stools

Question 13

Ig from mother to fetus

Answer 13

IgG

Question 14

treatment for Bruton’s

Answer 14

IVIG

Question 15

what opposes cytokines

Answer 15

transforming growth factor B

Question 16

Peyer’s Patches

Answer 16

IgA

MAC can get through these

Question 17

MHC II class

Answer 17

two alpha and two beta chains

Question 18

GvH timeline

Answer 18

weeks after transplant

Question 19

CD34

Answer 19

pluripotent stem cells

Question 20

CD27

Answer 20

plasma cells

Question 21

Acute rejection caused by

Answer 21

cytotoxic T cells

Question 22

breast milk

Answer 22

IgA

Question 23

CD40L dysfunction

Answer 23

hyper IgM syndrome

Question 24

where are T cells found

Answer 24

paracortex

Question 25

where are B cells found

Answer 25

follicle/germinal center

Question 26

MHC1 structure

Answer 26

alpha and B2 microglobulin

Question 27

MHC2 structure

Answer 27

alpha and beta

Question 28

NK enhanced by

Answer 28

IL-2 IL-12 IFN-B, IFN-alpha

Question 29

IgM and IgG

Answer 29

activate complement

Question 30

anti-inflamm cytokines

Answer 30

IL-10 | TGF-Beta

Question 31

pus

Answer 31

IL-8

Question 32

TNF-alpha

Answer 32

septic shock, leukocyte recuritment

Question 33

Interferon functions

Answer 33

inhibit viral protein synthesis increase MHC1 and 2 expression activate NK cells

Question 34

superantigens

Answer 34

cross link B region of TCR | massive release of cytokines

Question 35

endotoxins

Answer 35

stimulate macrophages by binding to endotoxin receptor CD14

Question 36

bacteria with antigen variation

Answer 36

salmonella borrelia n. gonorrhoea

Question 37

live vaccine

Answer 37

cellular response | MMR

Question 38

attenuated vaccin

Answer 38

humoral immunity | hep A

Question 39

Type II hypersen

Answer 39

CY-2-toxic IgM, IgG oponization, complemented mediated lysis, ADCC (NK cells)

Question 40

Type II hypersen

Answer 40

antigen-antibody-complement

Question 41

Type IV hypersen

Answer 41

T lymphocytes transplant rejections TB skin tests touching (contact dermatitis)

Question 42

Hyperacute transplant rxn

Answer 42

type II, preform anti-donor abs | occludes graft vessels

Question 43

Acute transplant rejection

Answer 43

weeks later cell mediated against foreign MHCs dense interstitial lymphocytic infiltrate

Question 44

CHronic transplant rejection

Answer 44

T cell and Ab mediated | obliterative vascular fibrosis