Immune System Missed Concepts Flashcards
cells with MHC1
all except RBCs
CD3
T cell
CD28
T cell
binds B7 on APC
CD4, 40
helper t cells
CD8
cytotoxic t cells
B cells
CD 19,20,21, 40
CD16
NK cells
CD56
NK cells
Anaphyaxis
C3a, C5a
Classic Complement pathways
IgG or IgM
APCs
dendritic cells
macrophages
B cells
Kaposi sarcoma associated with
black colored stools
Ig from mother to fetus
IgG
treatment for Bruton’s
IVIG
what opposes cytokines
transforming growth factor B
Peyer’s Patches
IgA
MAC can get through these
MHC II class
two alpha and two beta chains
GvH timeline
weeks after transplant
CD34
pluripotent stem cells
CD27
plasma cells
Acute rejection caused by
cytotoxic T cells
breast milk
IgA
CD40L dysfunction
hyper IgM syndrome
where are T cells found
paracortex
where are B cells found
follicle/germinal center
MHC1 structure
alpha and B2 microglobulin
MHC2 structure
alpha and beta
NK enhanced by
IL-2
IL-12
IFN-B, IFN-alpha
IgM and IgG
activate complement
anti-inflamm cytokines
IL-10
TGF-Beta
pus
IL-8
TNF-alpha
septic shock, leukocyte recuritment
Interferon functions
inhibit viral protein synthesis
increase MHC1 and 2 expression
activate NK cells
superantigens
cross link B region of TCR
massive release of cytokines
endotoxins
stimulate macrophages by binding to endotoxin receptor CD14
bacteria with antigen variation
salmonella
borrelia
n. gonorrhoea
live vaccine
cellular response
MMR
attenuated vaccin
humoral immunity
hep A
Type II hypersen
CY-2-toxic
IgM, IgG
oponization, complemented mediated lysis, ADCC (NK cells)
Type II hypersen
antigen-antibody-complement
Type IV hypersen
T lymphocytes
transplant rejections
TB skin tests
touching (contact dermatitis)
Hyperacute transplant rxn
type II, preform anti-donor abs
occludes graft vessels
Acute transplant rejection
weeks later
cell mediated against foreign MHCs
dense interstitial lymphocytic infiltrate
CHronic transplant rejection
T cell and Ab mediated
obliterative vascular fibrosis
