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First Aid Sections > Immune System Missed Concepts > Flashcards

Immune System Missed Concepts Flashcards

1
Q

cells with MHC1

A

all except RBCs

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2
Q

CD3

A

T cell

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3
Q

CD28

A

T cell

binds B7 on APC

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4
Q

CD4, 40

A

helper t cells

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5
Q

CD8

A

cytotoxic t cells

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6
Q

B cells

A

CD 19,20,21, 40

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7
Q

CD16

A

NK cells

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8
Q

CD56

A

NK cells

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9
Q

Anaphyaxis

A

C3a, C5a

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10
Q

Classic Complement pathways

A

IgG or IgM

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11
Q

APCs

A

dendritic cells
macrophages
B cells

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12
Q

Kaposi sarcoma associated with

A

black colored stools

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13
Q

Ig from mother to fetus

A

IgG

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14
Q

treatment for Bruton’s

A

IVIG

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15
Q

what opposes cytokines

A

transforming growth factor B

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16
Q

Peyer’s Patches

A

IgA

MAC can get through these

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17
Q

MHC II class

A

two alpha and two beta chains

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18
Q

GvH timeline

A

weeks after transplant

19
Q

CD34

A

pluripotent stem cells

20
Q

CD27

A

plasma cells

21
Q

Acute rejection caused by

A

cytotoxic T cells

22
Q

breast milk

23
Q

CD40L dysfunction

A

hyper IgM syndrome

24
Q

where are T cells found

A

paracortex

25
Q

where are B cells found

A

follicle/germinal center

26
Q

MHC1 structure

A

alpha and B2 microglobulin

27
Q

MHC2 structure

A

alpha and beta

28
Q

NK enhanced by

A

IL-2
IL-12
IFN-B, IFN-alpha

29
Q

IgM and IgG

A

activate complement

30
Q

anti-inflamm cytokines

A

IL-10

TGF-Beta

31
Q

pus

32
Q

TNF-alpha

A

septic shock, leukocyte recuritment

33
Q

Interferon functions

A

inhibit viral protein synthesis
increase MHC1 and 2 expression
activate NK cells

34
Q

superantigens

A

cross link B region of TCR

massive release of cytokines

35
Q

endotoxins

A

stimulate macrophages by binding to endotoxin receptor CD14

36
Q

bacteria with antigen variation

A

salmonella
borrelia
n. gonorrhoea

37
Q

live vaccine

A

cellular response

MMR

38
Q

attenuated vaccin

A

humoral immunity

hep A

39
Q

Type II hypersen

A

CY-2-toxic
IgM, IgG
oponization, complemented mediated lysis, ADCC (NK cells)

40
Q

Type II hypersen

A

antigen-antibody-complement

41
Q

Type IV hypersen

A

T lymphocytes
transplant rejections
TB skin tests
touching (contact dermatitis)

42
Q

Hyperacute transplant rxn

A

type II, preform anti-donor abs

occludes graft vessels

43
Q

Acute transplant rejection

A

weeks later
cell mediated against foreign MHCs
dense interstitial lymphocytic infiltrate

44
Q

CHronic transplant rejection

A

T cell and Ab mediated

obliterative vascular fibrosis

First Aid Sections (25 decks)

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