MICRO BIO Flashcards
C perfringens toxin
lecithinase/phospholipase C/alpha toxin
enterococci are resistant to
aminoglycosides
PAS
whipple’s disease
india ink
cryptococcus
silver stain
- fungi
- legionella
- h. pylori
chocolate agar with factors V and X
H influenzae
Thayer-Martin media
N gonorrhea
N meningitis
Bordet-Gengou agar
B. Pertussis
Loffler’s media
C diptheriae
Lowenstein-Jensen agar
M tuberculosis
Eaton’s agar
M. pneumoniae
charcoal yeast extract agar with cysteine and iron
Legionella
Sabouraud’s agar
fungi
yellow pigment
S aureus
Protein A
S. Aureus
binds Fc portion of Ig
IgA Protease
S pneumo, Hi influ, Neisseria
colonize resp mucosa
M protein
GAS, prevent phagocytosis
Exotoxin
tetanus, botulism, diphtheria
Endotoxin
meningococcemia
sepsis by GNR
diptheria toxin
inactivates EF-2
pseudomonas Exotoxin A
inactivates elongation factor 2
Shiga-like toxin
EHEC
inactivates 60s ribosome by removing adenine from rRNA
Pertussis toxin
overactives adenylate cyclase/cAMP
Tetanospasmin
cleaves SNARE protein for NT release
Botulinum toxin
cleaves SNARE protein for NT release
gas gangrene
Clostridium perfringens
Streptolysin O
degrades cell membrane
TSST-1
S aureus
overhwelming release of IFN gamma and IL-2 which leads to shock
Exotoxin A (s. pyogenes)
overwhelimg release of IFN gamma and IL-2 which leads to shock
ENDOTOXIN
edema, nitric oxide, DIC/death, outer membrane, TNF alpha, O-antigen, eXtremely heat stable, IL-1, neutrophil chemotaxis
Bacterial transformation
s pneumonia
h influenza
neiserria
S. aureus properties
catalase +
coagulase +
S. epidermis properties
catalse +
coagulase -
novobiocin +
S. saprophyticus properties
catalase +
coagulase -
novobiocin -
Strept pneumo shape
lancet-shaped, GP diplococci
Streptococccus agalactiae causes
GBS –> sepsis/meningitis in babies
Enterococci cause
UTI
biliary tract infections
subacute endocarditis
C. diff toxins
Toxin A - enterotoxin
Toxin B - destroys cytoskeletal structure of enterocytes - pseudomembranous colitis
polypeptide capsule
anthrax
Cutaneous anthrax toxins
lethal factor and edema factor
Bacillus cereus
rice
actinomyces treatment
penicillin
nocardia treatment
sulfonamdies
Lepromatous Leprosy
diffusely over skin
humoral TH2 response
Tuberculoid Leprosy
hairless skin plaques
TH1 immune response
tinea versicolor
Malassezia
hypopigmented patches
spaghettia and meatball apperance
tinea versicolor/malassezia
treatment for tinea versicolor
topical miconazole
selenium sulfide
treatment for vaginal candida
topical azole
treatment for oral/esophageal candida
fluconazole
capsofungin
treatment for systemic candida
fluconzaole
capsofungin
amph B
aflatoxin
aspergillua
cryptococcus found in
pigeon, soil droppings
soap bubble lesions in brain
cryptococcus
PCP treatment
TMP-SMX
Sporothrix schenckii
cigar shaped
gardener’s disease
S. schenckii treatment
itraconazole or potassiume iodide
Giardia
comes from water
fatty stools
metronidazole
Entamoeba histolytica
bloody diarrhea
comes from water
metronidazole
Cryptosporidum
AIDs
comes from water
prevent with nitazoxanide
congenital toxoplasmosis
chorioretinitis
hydrocephalus
intracranial calcifications
toxoplasma treatment
sulfadizaine + pyrimethamine
naegleria fowleri
rapidly fatal MEitis
freshwater lakes
Trypanosoma brucei
african sleeping sickess
tseste fly
Plasmodium/malaria treatment
chloroquine, mefloquine
quinidine if life threatening
primaquine for vivax/ovale
Babesia
Ixodes tick
maltese cross
treat with atovaquone
trypanosoma cruzi
chagas disese
reduviid bug
dilated cardiomyopathy, emgacolon, megaesophagus
leishmani donovani
leishmaniasis from sandfly
enterobius vermicularis treatment
bendazoles
ascaris lumbricoides treatment
bendazoles
strongyloides treatment
ivermectin or albendazole
loa loa
swelling in skin, worm in conjunctiva
treat with diethylcarbamazine