RECEPTORS

Question 1

what is the purpose of the nicotinic receptors?

Answer 1

skeletal muscle-ganglionic

Question 2

what is the purpose of the muscarinic receptors?

Answer 2

parasympathetic- post ganglionic

Question 3

agonist do what?

Answer 3

enhance transmission

Question 4

antagonist do what?

Answer 4

minimize transmission

Question 5

nicotinic agonists

Answer 5

ACh
nicotine
carbachol

Question 6

muscarinic agonists

Answer 6

ACh
muscarine
pilocarpine
oxotremorine

Question 7

nicotinic antagonist

Answer 7

curare
succinylcholine
rabies virus

Question 8

muscarinic antagonist

Answer 8

atropine

scopolamine

Question 9

what is the effect once the NT binds to the post synaptic receptor?

Answer 9

so its a conductance pore which, when opened, produces the EPP

Question 10

what proteins are used by the muscarinic receptors?

Answer 10

g-proteins

Question 11

what are the examples of the catecholaminergic receptors?

Answer 11

dopamine and adrenergic receptors

Question 12

this type of receptor has 5 subtypes of DA receptors and these stimulate 6 proteins and alter cAMP in target cells, name this receptor and the subtypes?

Answer 12

dopamine receptors

D1-D5 receptors

Question 13

what is the D1 family?

Answer 13

D1 and D5, stimulates G-protein in addition to adenylate cyclase to increase cAMP

Question 14

what is the D2 family?

Answer 14

D2, D3, D4 stimulates G-protein inhibitory inhibiting AC and this cAMP

Question 15

the D1 family is inhibited by?

Answer 15

bromocriptine

Question 16

the D2 family is inhibited by?

Answer 16

butyrophenone

Question 17

what are the D2 receptors associated with?

Answer 17

psychotic disorders and drugs which inhibit D2 receptors are used to treat the disorder

Question 18

where are the receptors for NE and EPI located?

Answer 18

CNS and PNS though we associate them with postganglionic target cells