ADRENERGIC RECEPTORS

Question 1

what are the adrenergic receptor subtypes

Answer 1

A1, A2, B1, B2, B3

Question 2

where are the A1 and A2 receptors located?

Answer 2

A1 receptors located everywhere else

A2 receptors located on the presynaptic vesicle

Question 3

where are the B1,B2,B3 receptors located?

Answer 3

B1 heart
B2 lung
B3 adipose

Question 4

what are the adrenergic receptor agonists?

Answer 4

EPI>NE and ephedrine

Question 5

what are the agonists and antagonists for the B receptors?

Answer 5

agonist is isoproterenol

antagonist is propranolol

Question 6

what is the agonist and antagonist for the B1 receptors specifically? also B2

Answer 6

B1
agonist is dobutamine
antagonist atenolol

B2
agonist is albuterol

Question 7

this receptor is found in most post ganglionic targets like blood vessels and acts to stimulate phospholipase C like DAG, IP3, and Ca

Answer 7

alpha 1

Question 8

this receptor is responsible for the presynaptic inhibition of nerve terminal and acts by inhibiting adenylate cyclase

Answer 8

alpha 2

Question 9

these receptors are found in the heart and cerebral cortex and act to stimulate adenylate cyclase. This increases heart rate and strength of contraction

Answer 9

Beta 1, first concern

Question 10

these receptors are found in the lungs and cerebellum and act to stimulate adenylate cyclase resulting in bronchodilator making it easier to breath?

Answer 10

Beta 2, second concern

Question 11

these receptors are the most recently identified subtype and drugs are not yet developed. Agonists would promote weight loss and increased body temperature

Answer 11

Beta 3