Purines (General + Drugs) Flashcards
1
Q
Adenosine CV Effects?
A
- Inhibits Cardiac Contraction
- Vasodilation
- Inhibits Platlet aggregation
2
Q
Adenosine CNS Effects?
A
Inhibits Neurons
3
Q
A1 Receptors
A
Pro-Inflammatory Effects
4
Q
A2 Receptors
A
Anti-Inflammatory Effects
5
Q
ADP
A
Acts on P2Y
- P2Y(12) = Platelet Aggregation
Anti-Platlet Drugs block ADP
6
Q
ATP
A
Acts on P2X
- Nociception
- Dead cells release ATP –> Inflammation
7
Q
Where is Adenosine found
A
Inside of Cells: Cytosol
Outside of Cells: Body Fluids
8
Q
Where is ADP found
A
Stored in Cell Vesicles
- Have to be exocytosed
9
Q
Where is ATP found
A
Present in Cells
- Have to be released through channels
- Have to be exocytosed
10
Q
Theophylline
A
Blocks A1 Receptor
- Asthma Treatment
11
Q
Caffeine
A
Adenosine Antagonist
- Stimulates neurons
