Anticoagulants (General)

Question 1

Clotting

Answer 1

Blood is converted into solid gels called:
- Thrombus / Clots

Occurs around platelets, reinforce plugs

Question 2

When are anticoagulants needed

Answer 2

Circulatory Stasis
- AFib
- Immobilization

Hypercoagulable State
- Pregnancy
- Malignancy

EC Trauma

Question 3

Clotting Factors and Platelets

Answer 3

Clotting Factors have gamma-carboxyglutamate residues (-) which bind to Ca2+ (+) which binds to Platelet (-)
- Ca2+ acts as bridge between Clotting Factor and Platelet